Forging a bond: an efficient, general palladium catalyst for C-O bond-forming reactions of secondary and primary alcohols with a range of aryl halides has been developed using the ligand 1. Heteroaryl halides, and for the first time, electron-rich aryl halides can be coupled with secondary alcohols. A diverse set of substrate combinations are possible with just a single ligand, thus obviating the need to survey multiple ligands.
Forging a bond: an efficient, general palladium catalyst for C-O bond-forming reactions of secondary and primary n class="Chemical">alcohols with a range of aryl halides has been developed using the ligand 1. Heteroaryl halides, and for the first time, electron-rich aryl halides can be coupled with secondary alcohols. A diverse set of substrate combinations are possible with just a single ligand, thus obviating the need to survey multiple ligands.
Authors: Donald A Watson; Mingjuan Su; Georgiy Teverovskiy; Yong Zhang; Jorge García-Fortanet; Tom Kinzel; Stephen L Buchwald Journal: Science Date: 2009-08-13 Impact factor: 47.728
Authors: Nathaniel H Park; Ekaterina V Vinogradova; David S Surry; Stephen L Buchwald Journal: Angew Chem Int Ed Engl Date: 2015-06-01 Impact factor: 15.336