Literature DB >> 21910409

Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic intervention.

Edward A Dennis1, Jian Cao, Yuan-Hao Hsu, Victoria Magrioti, George Kokotos.   

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Year:  2011        PMID： 21910409      PMCID： PMC3196595          DOI： 10.1021/cr200085w

Source DB:  PubMed          Journal:  Chem Rev        ISSN： 0009-2665            Impact factor:   60.622


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  664 in total

1.  Gene expression of group II phospholipase A2 in intestine in Crohn's disease.

Authors:  M M Haapamäki; J M Grönroos; H Nurmi; K Alanen; T J Nevalainen
Journal:  Am J Gastroenterol       Date:  1999-03       Impact factor: 10.864

2.  Human pancreatic islets express mRNA species encoding two distinct catalytically active isoforms of group VI phospholipase A2 (iPLA2) that arise from an exon-skipping mechanism of alternative splicing of the transcript from the iPLA2 gene on chromosome 22q13.1.

Authors:  Z Ma; X Wang; W Nowatzke; S Ramanadham; J Turk
Journal:  J Biol Chem       Date:  1999-04-02       Impact factor: 5.157

3.  Molecular cloning of two new human paralogs of 85-kDa cytosolic phospholipase A2.

Authors:  R T Pickard; B A Strifler; R M Kramer; J D Sharp
Journal:  J Biol Chem       Date:  1999-03-26       Impact factor: 5.157

4.  Deficiency of platelet-activating factor acetylhydrolase is a severity factor for asthma.

Authors:  D M Stafforini; T Numao; A Tsodikov; D Vaitkus; T Fukuda; N Watanabe; N Fueki; T M McIntyre; G A Zimmerman; S Makino; S M Prescott
Journal:  J Clin Invest       Date:  1999-04       Impact factor: 14.808

5.  The PLB2 gene of Saccharomyces cerevisiae confers resistance to lysophosphatidylcholine and encodes a phospholipase B/lysophospholipase.

Authors:  H Fyrst; B Oskouian; F A Kuypers; J D Saba
Journal:  Biochemistry       Date:  1999-05-04       Impact factor: 3.162

6.  Cell-wall determinants of the bactericidal action of group IIA phospholipase A2 against Gram-positive bacteria.

Authors:  A K Foreman-Wykert; Y Weinrauch; P Elsbach; J Weiss
Journal:  J Clin Invest       Date:  1999-03       Impact factor: 14.808

7.  Pharmacology of LY315920/S-5920, [[3-(aminooxoacetyl)-2-ethyl-1- (phenylmethyl)-1H-indol-4-yl]oxy] acetate, a potent and selective secretory phospholipase A2 inhibitor: A new class of anti-inflammatory drugs, SPI.

Authors:  D W Snyder; N J Bach; R D Dillard; S E Draheim; D G Carlson; N Fox; N W Roehm; C T Armstrong; C H Chang; L W Hartley; L M Johnson; C R Roman; A C Smith; M Song; J H Fleisch
Journal:  J Pharmacol Exp Ther       Date:  1999-03       Impact factor: 4.030

8.  Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a novel inhibitor.

Authors:  C H MacPhee; K E Moores; H F Boyd; D Dhanak; R J Ife; C A Leach; D S Leake; K J Milliner; R A Patterson; K E Suckling; D G Tew; D M Hickey
Journal:  Biochem J       Date:  1999-03-01       Impact factor: 3.857

9.  Molecular basis of the interaction between plasma platelet-activating factor acetylhydrolase and low density lipoprotein.

Authors:  D M Stafforini; L W Tjoelker; S P McCormick; D Vaitkus; T M McIntyre; P W Gray; S G Young; S M Prescott
Journal:  J Biol Chem       Date:  1999-03-12       Impact factor: 5.157

10.  Roles of Trp31 in high membrane binding and proinflammatory activity of human group V phospholipase A2.

Authors:  S K Han; K P Kim; R Koduri; L Bittova; N M Munoz; A R Leff; D C Wilton; M H Gelb; W Cho
Journal:  J Biol Chem       Date:  1999-04-23       Impact factor: 5.157
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  330 in total

1.  Synthesis and Evaluation of Cytosolic Phospholipase A(2) Activatable Fluorophores for Cancer Imaging.

Authors:  Michael G Chiorazzo; Noah B Bloch; Anatoliy V Popov; Edward J Delikatny
Journal:  Bioconjug Chem       Date:  2015-10-28       Impact factor: 4.774

2.  Is iPLA2β a Novel Target for the Development of New Strategies to Alleviate Inflammatory Bowel Disease?

Authors:  Toni Petan; Igor Križaj
Journal:  Dig Dis Sci       Date:  2015-12       Impact factor: 3.199

3.  Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A2 Type X (sPLA2-X) Inhibitors.

Authors:  Laurent Knerr; Fabrizio Giordanetto; Peter Nordberg; Daniel Pettersen; Nidhal Selmi; Hans-Georg Beisel; Hannah de la Motte; Thomas Olsson; Tim D J Perkins; Margareta Herslöf; Åsa Månsson; Mikael Dahlström; Ingemar Starke; Johan Broddefalk; Gabrielle Saarinen; Fredrik Klingegård; Eva Hurt-Camejo; Birgitta Rosengren; Johan Brengdahl; Frank Jansen; Mattias Rohman; Jenny Sandmark; Kenth Hallberg; Tomas Åkerud; Robert G Roth; Marie Ahlqvist
Journal:  ACS Med Chem Lett       Date:  2018-06-23       Impact factor: 4.345

Review 4.  Lysosomal phospholipase A2.

Authors:  James A Shayman; John J G Tesmer
Journal:  Biochim Biophys Acta Mol Cell Biol Lipids       Date:  2018-08-02       Impact factor: 4.698

5.  Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease.

Authors:  Luke Whiley; Arundhuti Sen; James Heaton; Petroula Proitsi; Diego García-Gómez; Rufina Leung; Norman Smith; Madhav Thambisetty; Iwona Kloszewska; Patrizia Mecocci; Hilkka Soininen; Magda Tsolaki; Bruno Vellas; Simon Lovestone; Cristina Legido-Quigley
Journal:  Neurobiol Aging       Date:  2013-09-13       Impact factor: 4.673

6.  Modeling of eicosanoid fluxes reveals functional coupling between cyclooxygenases and terminal synthases.

Authors:  Yasuyuki Kihara; Shakti Gupta; Mano R Maurya; Aaron Armando; Ishita Shah; Oswald Quehenberger; Christopher K Glass; Edward A Dennis; Shankar Subramaniam
Journal:  Biophys J       Date:  2014-02-18       Impact factor: 4.033

7.  Prostaglandin E2 Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages.

Authors:  Milena Sokolowska; Li-Yuan Chen; Yueqin Liu; Asuncion Martinez-Anton; Hai-Yan Qi; Carolea Logun; Sara Alsaaty; Yong Hwan Park; Daniel L Kastner; Jae Jin Chae; James H Shelhamer
Journal:  J Immunol       Date:  2015-04-27       Impact factor: 5.422

Review 8.  Cellular membrane fluidity in amyloid precursor protein processing.

Authors:  Xiaoguang Yang; Grace Y Sun; Gunter P Eckert; James C-M Lee
Journal:  Mol Neurobiol       Date:  2014-02-20       Impact factor: 5.590

9.  Conjugated linoleic acid-enriched butter improved memory and up-regulated phospholipase A2 encoding-genes in rat brain tissue.

Authors:  Marco A S Gama; Nádia R B Raposo; Fábio B Mury; Fernando C F Lopes; Emmanuel Dias-Neto; Leda L Talib; Wagner F Gattaz
Journal:  J Neural Transm (Vienna)       Date:  2015-04-26       Impact factor: 3.575

10.  2-Oxoamide inhibitors of cytosolic group IVA phospholipase A2 with reduced lipophilicity.

Authors:  Georgia Antonopoulou; Victoria Magrioti; Maroula G Kokotou; Aikaterini Nikolaou; Efrosini Barbayianni; Varnavas D Mouchlis; Edward A Dennis; George Kokotos
Journal:  Bioorg Med Chem       Date:  2016-07-27       Impact factor: 3.641
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