Literature DB >> 21909545

Triple helical recognition of pyrimidine inversions in polypurine tracts of RNA by nucleobase-modified PNA.

Pankaj Gupta1, Thomas Zengeya, Eriks Rozners.   

Abstract

Peptide nucleic acids containing 2-pyrimidinone (P) and 3-oxo-2,3-dihydropyridazine (E) heterocycles recognized C-G and U-A inversions in a polypurine tract of double helical RNA with high affinity and sequence selectivity at pH 6.25. E-modified PNA bound strongly to bacterial A-site RNA, while no binding was observed to the human A-site RNA.

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Year:  2011        PMID： 21909545      PMCID： PMC3757498          DOI： 10.1039/c1cc14706d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  24 in total

1.  A Structural Basis for RNAminus signLigand Interactions.

Authors:  Christine S. Chow; Felicia M. Bogdan
Journal:  Chem Rev       Date:  1997-08-05       Impact factor: 60.622

2.  Stable and selective recognition of three base pairs in the parallel triple-helical DNA binding motif.

Authors:  Sabrina Buchini; Christian J Leumann
Journal:  Angew Chem Int Ed Engl       Date:  2004-07-26       Impact factor: 15.336

Review 3.  Mechanisms of gene silencing by double-stranded RNA.

Authors:  Gunter Meister; Thomas Tuschl
Journal:  Nature       Date:  2004-09-16       Impact factor: 49.962

4.  Recognition of duplex RNA by helix-threading peptides.

Authors:  Barry D Gooch; Peter A Beal
Journal:  J Am Chem Soc       Date:  2004-09-01       Impact factor: 15.419

Review 5.  Sequence-selective targeting of duplex DNA by peptide nucleic acids.

Authors:  Peter E Nielsen
Journal:  Curr Opin Mol Ther       Date:  2010-04

6.  Micro RNAs in animal development.

Authors:  Ronald H A Plasterk
Journal:  Cell       Date:  2006-03-10       Impact factor: 41.582

7.  Macrocyclic helix-threading peptides for targeting RNA.

Authors:  Malathy Krishnamurthy; Kristina Simon; Anita M Orendt; Peter A Beal
Journal:  Angew Chem Int Ed Engl       Date:  2007       Impact factor: 15.336

Review 8.  An extra dimension in nucleic acid sequence recognition.

Authors:  Keith R Fox; Tom Brown
Journal:  Q Rev Biophys       Date:  2006-05-31       Impact factor: 5.318

9.  Short peptide nucleic acids bind strongly to homopurine tract of double helical RNA at pH 5.5.

Authors:  Ming Li; Thomas Zengeya; Eriks Rozners
Journal:  J Am Chem Soc       Date:  2010-06-30       Impact factor: 15.419

10.  A convenient route to N-[2-(Fmoc)aminoethyl]glycine esters and PNA oligomerization using a Bis-N-Boc nucleobase protecting group strategy.

Authors:  Filip Wojciechowski; Robert H E Hudson
Journal:  J Org Chem       Date:  2008-04-16       Impact factor: 4.354
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  17 in total

1.  Recognition of double-stranded RNA by guanidine-modified peptide nucleic acids.

Authors:  Pankaj Gupta; Oluwatoyosi Muse; Eriks Rozners
Journal:  Biochemistry       Date:  2011-12-20       Impact factor: 3.162

2.  Improvement of sequence selectivity in triple helical recognition of RNA by phenylalanine-derived PNA.

Authors:  Thomas Zengeya; Artem Gindin; Eriks Rozners
Journal:  Artif DNA PNA XNA       Date:  2013-10-08

3.  Comparison of microplate and macrodilution methods in time-kill study of new antimicrobial drugs.

Authors:  Ying Zhou; Zheng Hou; Chao Fang; Xiaoyan Xue; Fei Da; Yukun Wang; Hui Bai; Xiaoxing Luo
Journal:  Folia Microbiol (Praha)       Date:  2012-06-09       Impact factor: 2.099

4.  Fluorobenzene Nucleobase Analogues for Triplex-Forming Peptide Nucleic Acids.

Authors:  Vipin Kumar; Eriks Rozners
Journal:  Chembiochem       Date:  2021-12-20       Impact factor: 3.164

5.  Triple-helical recognition of RNA using 2-aminopyridine-modified PNA at physiologically relevant conditions.

Authors:  Thomas Zengeya; Pankaj Gupta; Eriks Rozners
Journal:  Angew Chem Int Ed Engl       Date:  2012-11-04       Impact factor: 15.336

6.  Thermal Stability of Peptide Nucleic Acid Complexes.

Authors:  Maciej Jasiński; Joanna Miszkiewicz; Michael Feig; Joanna Trylska
Journal:  J Phys Chem B       Date:  2019-09-20       Impact factor: 2.991

7.  Sequence selective recognition of double-stranded RNA at physiologically relevant conditions using PNA-peptide conjugates.

Authors:  Oluwatoyosi Muse; Thomas Zengeya; Juddy Mwaura; Dziyana Hnedzko; Dennis W McGee; Christof T Grewer; Eriks Rozners
Journal:  ACS Chem Biol       Date:  2013-06-12       Impact factor: 5.100

8.  Using triple-helix-forming Peptide nucleic acids for sequence-selective recognition of double-stranded RNA.

Authors:  Dziyana Hnedzko; Samwel K Cheruiyot; Eriks Rozners
Journal:  Curr Protoc Nucleic Acid Chem       Date:  2014-09-08

9.  Pyridazine Nucleobase in Triplex-Forming PNA Improves Recognition of Cytosine Interruptions of Polypurine Tracts in RNA.

Authors:  Nikita Brodyagin; Ilze Kumpina; Justin Applegate; Martins Katkevics; Eriks Rozners
Journal:  ACS Chem Biol       Date:  2021-04-21       Impact factor: 5.100

10.  Recent advances in chemical modification of Peptide nucleic acids.

Authors:  Eriks Rozners
Journal:  J Nucleic Acids       Date:  2012-09-06
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