PURPOSE: To evaluate phenotypic expressions of speech sound disorder (SSD) in multigenerational families with evidence of familial forms of SSD. METHOD: Members of five multigenerational families (N = 36) produced rapid sequences of monosyllables and disyllables and tapped computer keys with repetitive and alternating movements. RESULTS: Measures of repetitive and alternating motor speed were correlated within and between the two motor systems. Repetitive and alternating motor speeds increased in children and decreased in adults as a function of age. In two families with children who had severe speech deficits consistent with disrupted praxis, slowed alternating, but not repetitive, oral movements characterized most of the affected children and adults with a history of SSD, and slowed alternating hand movements were seen in some of the biologically related participants as well. CONCLUSION: Results are consistent with a familial motor-based SSD subtype with incomplete penetrance, motivating new clinical questions about motor-based intervention not only in the oral but also the limb system.
PURPOSE: To evaluate phenotypic expressions of speech sound disorder (SSD) in multigenerational families with evidence of familial forms of SSD. METHOD: Members of five multigenerational families (N = 36) produced rapid sequences of monosyllables and disyllables and tapped computer keys with repetitive and alternating movements. RESULTS: Measures of repetitive and alternating motor speed were correlated within and between the two motor systems. Repetitive and alternating motor speeds increased in children and decreased in adults as a function of age. In two families with children who had severe speech deficits consistent with disrupted praxis, slowed alternating, but not repetitive, oral movements characterized most of the affected children and adults with a history of SSD, and slowed alternating hand movements were seen in some of the biologically related participants as well. CONCLUSION: Results are consistent with a familial motor-based SSD subtype with incomplete penetrance, motivating new clinical questions about motor-based intervention not only in the oral but also the limb system.
Authors: Thomas F Campbell; Christine A Dollaghan; Howard E Rockette; Jack L Paradise; Heidi M Feldman; Lawrence D Shriberg; Diane L Sabo; Marcia Kurs-Lasky Journal: Child Dev Date: 2003 Mar-Apr
Authors: Barbara A Lewis; Lisa A Freebairn; Amy J Hansen; Lara Miscimarra; Sudha K Iyengar; H Gerry Taylor Journal: Am J Speech Lang Pathol Date: 2007-05 Impact factor: 2.408
Authors: Anna Maria Chilosi; Irina Podda; Ivana Ricca; Alessandro Comparini; Beatrice Franchi; Simona Fiori; Rosa Pasquariello; Claudia Casalini; Paola Cipriani; Filippo Maria Santorelli Journal: J Pers Med Date: 2022-02-19
Authors: Beate Peter; Ellen M Wijsman; Alejandro Q Nato; Mark M Matsushita; Kathy L Chapman; Ian B Stanaway; John Wolff; Kaori Oda; Virginia B Gabo; Wendy H Raskind Journal: PLoS One Date: 2016-04-27 Impact factor: 3.240