| Literature DB >> 21904658 |
Kyoichi Kaira, Noboru Oriuchi, Noriaki Sunaga, Tamotsu Ishizuka, Kimihiro Shimizu, Nobuyuki Yamamoto.
Abstract
Positron emission tomography imaging with 2-[fluorine-18]-fluoro-2-deoxy-D-glucose ((18)F-FDG) has been established as a significant molecular imaging technique in the management of lung cancer. However, (18)F-FDG accumulation is not specific, therefore several other radiotracers targeting hypoxia, cell proliferation and amino acid metabolism have been developed for the imaging of human cancers. This review summarizes the current data on the correlation between the underlying molecular biology and tumor PET accumulation in lung cancer.Entities:
Keywords: 18F-FDG; Molecular biology; PET; cell metabolism; hypoxia; lung cancer; molecular imaging; proliferation
Year: 2011 PMID: 21904658 PMCID: PMC3158740
Source DB: PubMed Journal: Am J Transl Res Impact factor: 4.060