OBJECTIVES: The aim of this study was to examine the relation between hostility and incident ischemic heart disease (IHD) and to determine whether observed hostility is superior to patient-reported hostility for the prediction of IHD in a large, prospective observational study. BACKGROUND: Some studies have found that hostile patients have an increased risk of incident IHD. However, no studies have compared methods of hostility assessment or considered important psychosocial and cardiovascular risk factors as confounders. Furthermore, it is unknown whether all expressions of hostility carry equal risk or whether certain manifestations are more cardiotoxic. METHODS: We assessed the independent relationship between baseline observed hostility and 10-year incident IHD in 1,749 adults of the population-based Canadian Nova Scotia Health Survey. RESULTS: There were 149 (8.5%) incident IHD events (140 nonfatal, 9 fatal) during the 15,295 person-years of observation (9.74 events/1,000 person-years). Participants with any observed hostility had a greater risk of incident IHD than those without (p = 0.02); no such relation was found for patient-reported hostility. Those with any observed hostility had a significantly greater risk of incident IHD (hazard ratio: 2.06, 95% confidence interval: 1.04 to 4.08, p = 0.04), after adjusting for cardiovascular (age, sex, Framingham Risk Score) and psychosocial (depression, positive affect, patient-reported hostility, and anger) risk factors. CONCLUSIONS: The presence of any observed hostility at baseline was associated with a 2-fold increased risk of incident IHD over 10 years of follow-up. Compared with patient-reported measures, observed hostility is a superior predictor of IHD.
OBJECTIVES: The aim of this study was to examine the relation between hostility and incident ischemic heart disease (IHD) and to determine whether observed hostility is superior to patient-reported hostility for the prediction of IHD in a large, prospective observational study. BACKGROUND: Some studies have found that hostile patients have an increased risk of incident IHD. However, no studies have compared methods of hostility assessment or considered important psychosocial and cardiovascular risk factors as confounders. Furthermore, it is unknown whether all expressions of hostility carry equal risk or whether certain manifestations are more cardiotoxic. METHODS: We assessed the independent relationship between baseline observed hostility and 10-year incident IHD in 1,749 adults of the population-based Canadian Nova Scotia Health Survey. RESULTS: There were 149 (8.5%) incident IHD events (140 nonfatal, 9 fatal) during the 15,295 person-years of observation (9.74 events/1,000 person-years). Participants with any observed hostility had a greater risk of incident IHD than those without (p = 0.02); no such relation was found for patient-reported hostility. Those with any observed hostility had a significantly greater risk of incident IHD (hazard ratio: 2.06, 95% confidence interval: 1.04 to 4.08, p = 0.04), after adjusting for cardiovascular (age, sex, Framingham Risk Score) and psychosocial (depression, positive affect, patient-reported hostility, and anger) risk factors. CONCLUSIONS: The presence of any observed hostility at baseline was associated with a 2-fold increased risk of incident IHD over 10 years of follow-up. Compared with patient-reported measures, observed hostility is a superior predictor of IHD.
Authors: Lijing L Yan; Kiang Liu; Karen A Matthews; Martha L Daviglus; T Freeman Ferguson; Catarina I Kiefe Journal: JAMA Date: 2003-10-22 Impact factor: 56.272
Authors: Karina W Davidson; Matthew M Burg; Ian M Kronish; Daichi Shimbo; Lucia Dettenborn; Roxana Mehran; David Vorchheimer; Lynn Clemow; Joseph E Schwartz; Francois Lespérance; Nina Rieckmann Journal: Arch Gen Psychiatry Date: 2010-05
Authors: Parisa Hajjari; Sara Mattsson; Kathleen M McIntyre; Paula S McKinley; Peter A Shapiro; Ethan E Gorenstein; Felice A Tager; Chien-Wen J Choi; Seonjoo Lee; Richard P Sloan Journal: Psychosom Med Date: 2016-05 Impact factor: 4.312
Authors: Elena Salmoirago-Blotcher; Kathleen M Hovey; Cristopher A Andrews; Matthew Allison; Robert L Brunner; Nathalie L Denburg; Charles Eaton; Lorena Garcia; Shawnita M Sealy-Jefferson; Oleg Zaslavsky; Joseph Kang; Lenny López; Stephen G Post; Hilary Tindle; Sylvia Wassertheil-Smoller Journal: Psychosom Med Date: 2019-04 Impact factor: 4.312
Authors: Jonathan A Shaffer; Lauren Taggart Wasson; Karina W Davidson; Joseph E Schwartz; Susan Kirkland; Daichi Shimbo Journal: Int J Hypertens Date: 2012-02-08 Impact factor: 2.420
Authors: John M Ruiz; Daniel J Taylor; Bert N Uchino; Timothy W Smith; Matthew Allison; Chul Ahn; Jillian J Johnson; Joshua M Smyth Journal: BMJ Open Date: 2017-08-14 Impact factor: 2.692