Literature DB >> 21899318

Nanoparticles targeting the infarcted heart.

Tal Dvir1, Michael Bauer, Avi Schroeder, Jonathan H Tsui, Daniel G Anderson, Robert Langer, Ronglih Liao, Daniel S Kohane.   

Abstract

We report a nanoparticulate system capable of targeting the heart after myocardial infarction (MI). Targeting is based on overexpression of angiotensin II type 1 (AT1) receptor in the infarcted heart. Liposomes 142 nm in diameter were conjugated with a ligand specific to AT1. The nanoparticles were able to specifically target cardiac cells in vitro, and in the infarcted heart after intravenous injection in vivo. This system may be useful for delivering therapeutic agents specifically to the infarcted heart.

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Year:  2011        PMID： 21899318      PMCID： PMC3192253          DOI： 10.1021/nl2025882

Source DB:  PubMed          Journal:  Nano Lett        ISSN： 1530-6984            Impact factor:   11.189


  25 in total

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2.  Activation of the ERK1/2 cascade via pulsatile interstitial fluid flow promotes cardiac tissue assembly.

Authors:  Tal Dvir; Oren Levy; Michal Shachar; Yosef Granot; Smadar Cohen
Journal:  Tissue Eng       Date:  2007-09

3.  A novel perfusion bioreactor providing a homogenous milieu for tissue regeneration.

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Journal:  Tissue Eng       Date:  2006-10

4.  Controlled delivery of PDGF-BB for myocardial protection using injectable self-assembling peptide nanofibers.

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5.  Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo.

Authors:  Omid C Farokhzad; Jianjun Cheng; Benjamin A Teply; Ines Sherifi; Sangyong Jon; Philip W Kantoff; Jerome P Richie; Robert Langer
Journal:  Proc Natl Acad Sci U S A       Date:  2006-04-10       Impact factor: 11.205

6.  Modulation of cardiac macrophages by phosphatidylserine-presenting liposomes improves infarct repair.

Authors:  Tamar Harel-Adar; Tamar Ben Mordechai; Yoram Amsalem; Micha S Feinberg; Jonathan Leor; Smadar Cohen
Journal:  Proc Natl Acad Sci U S A       Date:  2011-01-18       Impact factor: 11.205

7.  Cardioprotective effects of rosiglitazone are associated with selective overexpression of type 2 angiotensin receptors and inhibition of p42/44 MAPK.

Authors:  Behzad Molavi; Jiawei Chen; J L Mehta
Journal:  Am J Physiol Heart Circ Physiol       Date:  2006-03-31       Impact factor: 4.733

8.  Brain endo-oligopeptidase B: a post-proline cleaving enzyme that inactivates angiotensin I and II.

Authors:  L J Greene; A C Spadaro; A R Martins; W D Perussi De Jesus; A C Camargo
Journal:  Hypertension       Date:  1982 Mar-Apr       Impact factor: 10.190

9.  Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair.

Authors:  Bernhard Kühn; Federica del Monte; Roger J Hajjar; Yuh-Shin Chang; Djamel Lebeche; Shima Arab; Mark T Keating
Journal:  Nat Med       Date:  2007-07-15       Impact factor: 53.440

Review 10.  Monoclonal antibody therapy for cancer.

Authors:  Margaret von Mehren; Gregory P Adams; Louis M Weiner
Journal:  Annu Rev Med       Date:  2001-12-03       Impact factor: 13.739
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  55 in total

1.  The cargo of CRPPR-conjugated liposomes crosses the intact murine cardiac endothelium.

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Journal:  J Control Release       Date:  2012-07-07       Impact factor: 9.776

2.  Drug Delivery and Nanoformulations for the Cardiovascular System.

Authors:  W J Geldenhuys; M T Khayat; J Yun; M A Nayeem
Journal:  Res Rev Drug Deliv       Date:  2017-03-07

Review 3.  Potential Strategies to Reduce Blood Pressure in Treatment-Resistant Hypertension Using Food and Drug Administration-Approved Nanodrug Delivery Platforms.

Authors:  Ibra S Fancher; Israel Rubinstein; Irena Levitan
Journal:  Hypertension       Date:  2019-02       Impact factor: 10.190

Review 4.  Getting Drugs Across Biological Barriers.

Authors:  Rong Yang; Tuo Wei; Hannah Goldberg; Weiping Wang; Kathleen Cullion; Daniel S Kohane
Journal:  Adv Mater       Date:  2017-07-28       Impact factor: 30.849

5.  Platelet-Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury.

Authors:  Teng Su; Ke Huang; Hong Ma; Hongxia Liang; Phuong-Uyen Dinh; Justin Chen; Deliang Shen; Tyler A Allen; Li Qiao; Zhenhua Li; Shiqi Hu; Jhon Cores; Brianna N Frame; Ashlyn T Young; Qi Yin; Jiandong Liu; Li Qian; Thomas G Caranasos; Yevgeny Brudno; Frances S Ligler; Ke Cheng
Journal:  Adv Funct Mater       Date:  2018-11-13       Impact factor: 18.808

6.  Nanoparticles administered intrapericardially enhance payload myocardial distribution and retention.

Authors:  Victor Segura-Ibarra; Francisca E Cara; Suhong Wu; David A Iruegas-Nunez; Sufen Wang; Mauro Ferrari; Arturas Ziemys; Miguel Valderrabano; Elvin Blanco
Journal:  J Control Release       Date:  2017-07-09       Impact factor: 9.776

7.  BaTiO3-core Au-shell nanoparticles for photothermal therapy and bimodal imaging.

Authors:  Yanfei Wang; Aoune Barhoumi; Rong Tong; Weiping Wang; Tianjiao Ji; Xiaoran Deng; Lele Li; Sophie A Lyon; Gally Reznor; David Zurakowski; Daniel S Kohane
Journal:  Acta Biomater       Date:  2018-03-22       Impact factor: 8.947

8.  Micro- and Nanoparticles for Treating Cardiovascular Disease.

Authors:  S Suarez; A Almutairi; K L Christman
Journal:  Biomater Sci       Date:  2015-04       Impact factor: 6.843

Review 9.  Materials to clinical devices: technologies for remotely triggered drug delivery.

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Journal:  Clin Ther       Date:  2012-11       Impact factor: 3.393

10.  A specifically designed nanoconstruct associates, internalizes, traffics in cardiovascular cells, and accumulates in failing myocardium: a new strategy for heart failure diagnostics and therapeutics.

Authors:  Guillermo U Ruiz-Esparza; Victor Segura-Ibarra; Andrea M Cordero-Reyes; Keith A Youker; Rita E Serda; Ana S Cruz-Solbes; Javier Amione-Guerra; Kenji Yokoi; Dickson K Kirui; Francisca E Cara; Jesus Paez-Mayorga; Jose H Flores-Arredondo; Carlos E Guerrero-Beltrán; Gerardo Garcia-Rivas; Mauro Ferrari; Elvin Blanco; Guillermo Torre-Amione
Journal:  Eur J Heart Fail       Date:  2016-01-07       Impact factor: 15.534
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