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Literature DB >> 28752600

Getting Drugs Across Biological Barriers.

Rong Yang¹, Tuo Wei¹, Hannah Goldberg¹, Weiping Wang¹, Kathleen Cullion¹, Daniel S Kohane¹.

Abstract

The delivery of drugs to a target site frequently involves crossing biological barriers. The degree and nature of the impediment to flux, as well as the potential approaches to overcoming it, depend on the tissue, the drug, and numerous other factors. Here an overview of approaches that have been taken to crossing biological barriers is presented, with special attention to transdermal drug delivery. Technology and knowledge pertaining to addressing these issues in a variety of organs could have a significant clinical impact.

Entities: Chemical Disease Gene Species

Keywords: biological barriers; drug delivery; transdermal transport

Mesh：

Substances：

Year: 2017 PMID： 28752600 PMCID： PMC5683089 DOI： 10.1002/adma.201606596

Source DB: PubMed Journal: Adv Mater ISSN： 0935-9648 Impact factor: 30.849

263 in total

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Journal: J Pharm Sci Date: 1998-12 Impact factor: 3.534

Review 2. Future of the transdermal drug delivery market--have we barely touched the surface?

Authors: Adam C Watkinson; Mary-Carmel Kearney; Helen L Quinn; Aaron J Courtenay; Ryan F Donnelly
Journal: Expert Opin Drug Deliv Date: 2015-12-28 Impact factor: 6.648

Review 3. Ultrasonic drug delivery--a general review.

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Journal: Expert Opin Drug Deliv Date: 2004-11 Impact factor: 6.648

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Authors: Renata F V Lopez; Jennifer E Seto; Daniel Blankschtein; Robert Langer
Journal: Biomaterials Date: 2010-10-23 Impact factor: 12.479

Review 5. Ultrasound mediated transdermal drug delivery.

Authors: Aharon Azagury; Luai Khoury; Giora Enden; Joseph Kost
Journal: Adv Drug Deliv Rev Date: 2014-01-22 Impact factor: 15.470

6. Systematic review of N-acetylcysteine in cystic fibrosis.

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Journal: Acta Paediatr Date: 1999-01 Impact factor: 2.299

7. Description of transdermal transport of hydrophilic solutes during low-frequency sonophoresis based on a modified porous pathway model.

Authors: Ahmet Tezel; Ashley Sens; Samir Mitragotri
Journal: J Pharm Sci Date: 2003-02 Impact factor: 3.534

8. Topical delivery of methotrexate via skin pretreated with physical enhancement techniques: low-fluence erbium:YAG laser and electroporation.

Authors: Woan-Ruoh Lee; Shin-Chuan Shen; Chia-Lang Fang; Rou-Zi Zhuo; Jia-You Fang
Journal: Lasers Surg Med Date: 2008-09 Impact factor: 4.025

Review 9. Nanoparticle therapeutics: an emerging treatment modality for cancer.

Authors: Mark E Davis; Zhuo Georgia Chen; Dong M Shin
Journal: Nat Rev Drug Discov Date: 2008-09 Impact factor: 84.694

10. Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome.

Authors: Benoit Chassaing; Omry Koren; Julia K Goodrich; Angela C Poole; Shanthi Srinivasan; Ruth E Ley; Andrew T Gewirtz
Journal: Nature Date: 2015-02-25 Impact factor: 49.962

25 in total

Review 1. Recent advances in understanding oligonucleotide aptamers and their applications as therapeutic agents.

Authors: Khaled S Allemailem; Ahmad Almatroudi; Mohammed A Alsahli; Ghaiyda Talal Basfar; Faris Alrumaihi; Arshad Husain Rahmani; Amjad Ali Khan
Journal: 3 Biotech Date: 2020-11-24 Impact factor: 2.406

2. Transtympanic Delivery of Local Anesthetics for Pain in Acute Otitis Media.

Authors: Rong Yang; Riitta Saarinen; Obiajulu S Okonkwo; Yi Hao; Manisha Mehta; Daniel S Kohane
Journal: Mol Pharm Date: 2019-03-06 Impact factor: 4.939

3. Single Application Cold-Chain Independent Drug Delivery System for Outer Ear Infections.

Authors: Bogdan A Serban; Kevin Shi; Jeremy B Alverson; John Hoody; Nigel D Priestley; Albert H Park; Monica A Serban
Journal: ACS Biomater Sci Eng Date: 2020-09-03

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Authors: Yuqi Zhang; Jicheng Yu; Anna R Kahkoska; Jinqiang Wang; John B Buse; Zhen Gu
Journal: Adv Drug Deliv Rev Date: 2018-12-08 Impact factor: 15.470

Review 5. Polymeric nanoparticles in the diagnosis and treatment of myocardial infarction: Challenges and future prospects.

Authors: Mia Karam; Duaa Fahs; Batoul Maatouk; Brouna Safi; Ayad A Jaffa; Rami Mhanna
Journal: Mater Today Bio Date: 2022-04-04

Review 6. Application of Mathematical Modeling and Computational Tools in the Modern Drug Design and Development Process.

Authors: Md Rifat Hasan; Ahad Amer Alsaiari; Burhan Zain Fakhurji; Mohammad Habibur Rahman Molla; Amer H Asseri; Md Afsar Ahmed Sumon; Moon Nyeo Park; Foysal Ahammad; Bonglee Kim
Journal: Molecules Date: 2022-06-29 Impact factor: 4.927