Literature DB >> 21892775

Arachnoid ossificans containing metaplastic hematopoietic marrow resulting in diffuse thoracic intrathecal cysts and severe myelopathy.

Joshua Abrams1, Gordon Li, Stefan A Mindea, Claudia M Haynes, Ivan Cheng.   

Abstract

OBJECTIVE: To present a rare case of multiple compressive thoracic intradural cysts with pathologic arachnoid ossification, review the literature and present the surgical options. Few reports have identified the existence of arachnoid calcifications and intrathecal cysts causing progressive myelopathy. The literature regarding each of these pathologies is limited to case reports. Their clinical significance is not well studied, although known to cause neurologic sequelae.
METHODS: An 81-year-old female clinically presents with rapidly progressive myelopathy. Pre-operative magnetic resonance imaging identified multiple compressive thoracic intrathecal cysts. Surgical exploration and decompression of these cysts identified calcified plaques within the arachnoid. Histopathologic examination revealed fibrocalcific tissue undergoing ossification with bone marrow elements.
RESULTS: Due to progressive myelopathy, the thoracic cysts were decompressed and calcified plaques were excised, once identified intra-operatively.
CONCLUSIONS: On last examination, the patient's neurologic status had not improved, but had stabilized. The rate of neurologic improvement from excision and decompression is variable, but it may still be warranted in the face of progressive neurologic deficits.

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Mesh:

Year:  2011        PMID: 21892775      PMCID: PMC3369052          DOI: 10.1007/s00586-011-2005-1

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  23 in total

Review 1.  Spinal extradural arachnoid cyst--case report.

Authors:  S Hatashita; A Kondo; T Shimizu; A Kurosu; H Ueno
Journal:  Neurol Med Chir (Tokyo)       Date:  2001-06       Impact factor: 1.742

2.  Multiple extradural arachnoid cysts at the spinal cord and cauda equina levels in the young.

Authors:  T Takagaki; T Nomura; E Toh; M Watanabe; J Mochida
Journal:  Spinal Cord       Date:  2006-01       Impact factor: 2.772

3.  Arachnoiditis ossificans.

Authors:  C R Barthelemy
Journal:  J Comput Assist Tomogr       Date:  1982-08       Impact factor: 1.826

4.  Clinicopathological considerations in spinal meningeal calcification and ossification.

Authors:  A B Kaufman; R H Dunsmore
Journal:  Neurology       Date:  1971-12       Impact factor: 9.910

5.  Arachnoiditis ossificans and syringomyelia: a unique case report.

Authors:  R J Kahler; N W Knuckey; S Davis
Journal:  J Clin Neurosci       Date:  2000-01       Impact factor: 1.961

6.  Diffuse arachnoid ossification and multiple arachnoid cysts presenting with progressive thoracic myelopathy.

Authors:  Toshinori Sakai; Koichi Sairyo; Masahiro Kashima; Hirofumi Kosaka; Shinsuke Katoh; Natsuo Yasui
Journal:  Skeletal Radiol       Date:  2009-12-04       Impact factor: 2.199

7.  Spinal arachnoid cysts: clinical and radiological correlation with prognosis.

Authors:  B E Kendall; A R Valentine; B Keis
Journal:  Neuroradiology       Date:  1982       Impact factor: 2.804

8.  Arachnoiditis ossificans. Report of a case.

Authors:  L Nainkin
Journal:  Spine (Phila Pa 1976)       Date:  1978-03       Impact factor: 3.468

9.  Lumbosacral arachnoiditis.

Authors:  C V Burton
Journal:  Spine (Phila Pa 1976)       Date:  1978-03       Impact factor: 3.468

10.  Arachnoiditis ossificans with progressive syringomyelia and spinal arachnoid cyst.

Authors:  F Papavlasopoulos; G Stranjalis; A T Kouyialis; S Korfias; D Sakas
Journal:  J Clin Neurosci       Date:  2007-03-23       Impact factor: 1.961

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  1 in total

1.  Arachnoiditis Ossificans - A Rare Cause of Progressive Myelopathy.

Authors:  Christopher J Steel; Erik L Abrames; William T O'Brien
Journal:  Open Neuroimag J       Date:  2015-08-31
  1 in total

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