Literature DB >> 2189110

A member of the ras gene superfamily is expressed specifically in T, B and myeloid hemopoietic cells.

N V Shirsat1, R J Pignolo, B L Kreider, G Rovera.   

Abstract

A 1.26 kb murine cDNA having 31% homology with human ras and 55% homology with human rho proteins was isolated using an oligonucleotide probe homologous to catalytic subdomain of a tyrosine kinase subfamily. Northern blot analysis indicates that the expression of the murine gene is restricted to the cells of hemopoietic lineages and the mRNA levels increase with the terminal differentiation of hemopoietic cells into granulocytes.

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Year:  1990        PMID： 2189110

Source DB:  PubMed          Journal:  Oncogene        ISSN： 0950-9232            Impact factor:   9.867


  30 in total

1.  On how Rac controls hematopoietic stem cell activity.

Authors:  J A Cancelas
Journal:  Transfusion       Date:  2011-11       Impact factor: 3.157

2.  Inhibition of tumor cell migration and invasion through knockdown of Rac1 expression in medulloblastoma cells.

Authors:  Baodong Chen; Yongzhong Gao; Taipeng Jiang; Jianjun Ding; Yanjun Zeng; Ruxiang Xu; Xiaodan Jiang
Journal:  Cell Mol Neurobiol       Date:  2010-11-13       Impact factor: 5.046

3.  Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton.

Authors:  Theodosia A Kalfa; Suvarnamala Pushkaran; Narla Mohandas; John H Hartwig; Velia M Fowler; James F Johnson; Clinton H Joiner; David A Williams; Yi Zheng
Journal:  Blood       Date:  2006-08-01       Impact factor: 22.113

4.  Rac1-null mouse embryonic fibroblasts are motile and respond to platelet-derived growth factor.

Authors:  Luis Vidali; Feng Chen; Gregor Cicchetti; Yasutaka Ohta; David J Kwiatkowski
Journal:  Mol Biol Cell       Date:  2006-03-08       Impact factor: 4.138

5.  Multiplex messenger assay: simultaneous, quantitative measurement of expression of many genes in the context of T cell activation.

Authors:  K Bernard; N Auphan; S Granjeaud; G Victorero; A M Schmitt-Verhulst; B R Jordan; C Nguyen
Journal:  Nucleic Acids Res       Date:  1996-04-15       Impact factor: 16.971

Review 6.  Rho GTPases control specific cytoskeleton-dependent functions of hematopoietic stem cells.

Authors:  Ramesh C Nayak; Kyung-Hee Chang; Nataraja-Sarma Vaitinadin; Jose A Cancelas
Journal:  Immunol Rev       Date:  2013-11       Impact factor: 12.988

7.  Rac GTPases in erythroid biology.

Authors:  D G Konstantinidis; A George; T A Kalfa
Journal:  Transfus Clin Biol       Date:  2010-07-23       Impact factor: 1.406

8.  Rac1 promotes intestinal epithelial restitution by increasing Ca2+ influx through interaction with phospholipase C-(gamma)1 after wounding.

Authors:  Jaladanki N Rao; Stephen V Liu; Tongtong Zou; Lan Liu; Lan Xiao; Xian Zhang; Emily Bellavance; Jason X-J Yuan; Jian-Ying Wang
Journal:  Am J Physiol Cell Physiol       Date:  2008-10-15       Impact factor: 4.249

9.  Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development.

Authors:  Fukun Guo; Jose A Cancelas; David Hildeman; David A Williams; Yi Zheng
Journal:  Blood       Date:  2008-06-25       Impact factor: 22.113

10.  A Rac1 inhibitory peptide suppresses antibody production and paw swelling in the murine collagen-induced arthritis model of rheumatoid arthritis.

Authors:  Joana Rf Abreu; Wendy Dontje; Sarah Krausz; Daphne de Launay; Paula B van Hennik; Anne-Marieke van Stalborch; Jean-Paul Ten Klooster; Marjolein E Sanders; Kris A Reedquist; Margriet J Vervoordeldonk; Peter L Hordijk; Paul P Tak
Journal:  Arthritis Res Ther       Date:  2010-01-06       Impact factor: 5.156
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