Literature DB >> 21887453

Click-chemistry approach to isoxazole-containing α-CF3-substituted α-aminocarboxylates and α-aminophosphonates.

Daria V Vorobyeva1, Natalya M Karimova, Irina L Odinets, Gerd-Volker Röschenthaler, Sergey N Osipov.   

Abstract

A convenient strategy for the synthesis of isoxazole-containing α-CF(3)-substituted α-aminocarboxylates and α-aminophosphonates have been developed. The method is based on copper-catalyzed 1,3-dipolar cycloaddition of different aromatic nitrile oxides to functionalized acetylenes.

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Year:  2011        PMID： 21887453     DOI： 10.1039/c1ob06040f

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  4 in total

1.  Induction of apoptosis and downregulation of ERα in DMBA-induced mammary gland tumors in Sprague-Dawley rats by synthetic 3,5-disubstituted isoxazole derivatives.

Authors:  Hanumappa Ananda; Kothanahally S Sharath Kumar; Mahesh Hegde; Kanchugarakoppal S Rangappa
Journal:  Mol Cell Biochem       Date:  2016-07-29       Impact factor: 3.396

2.  Synthesis and biological evaluation of novel flavone/triazole/benzimidazole hybrids and flavone/isoxazole-annulated heterocycles as antiproliferative and antimycobacterial agents.

Authors:  Yerrabelly Jayaprakash Rao; Thummala Sowjanya; Gogula Thirupathi; Nandula Yadagiri Sreenivasa Murthy; Sudha Sravanti Kotapalli
Journal:  Mol Divers       Date:  2018-06-04       Impact factor: 2.943

Review 3.  Artificial sugar saccharin and its derivatives: role as a catalyst.

Authors:  Kamalpreet Kaur; Suman Srivastava
Journal:  RSC Adv       Date:  2020-10-06       Impact factor: 4.036

4.  Demonstration of the utility of DOS-derived fragment libraries for rapid hit derivatisation in a multidirectional fashion.

Authors:  Sarah L Kidd; Elaine Fowler; Till Reinhardt; Thomas Compton; Natalia Mateu; Hector Newman; Dom Bellini; Romain Talon; Joseph McLoughlin; Tobias Krojer; Anthony Aimon; Anthony Bradley; Michael Fairhead; Paul Brear; Laura Díaz-Sáez; Katherine McAuley; Hannah F Sore; Andrew Madin; Daniel H O'Donovan; Kilian V M Huber; Marko Hyvönen; Frank von Delft; Christopher G Dowson; David R Spring
Journal:  Chem Sci       Date:  2020-05-14       Impact factor: 9.825
  4 in total

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