Literature DB >> 2188590

Randomized, controlled trial of a 10-day course of amifloxacin versus trimethoprim-sulfamethoxazole in the treatment of acute, uncomplicated urinary tract infection. Amifloxacin Multi-Center Trial Group.

E J Boyko1, A Iravani, M H Silverman, D J Schelling, R A Wright.   

Abstract

We conducted a randomized controlled trial of orally administered amifloxacin versus trimethoprimsulfamethoxazole (TMP-SMX) as treatments of acute uncomplicated urinary tract infection in women. Amifloxacin at a dosage of 200 mg twice a day appeared as safe and effective as TMP-SMX, but amifloxacin at 400 mg twice a day tended to cause adverse events more frequently than did TMP-SMX.

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Year:  1990        PMID： 2188590      PMCID： PMC171664          DOI： 10.1128/AAC.34.4.665

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

1.  Confidence intervals for reporting results of clinical trials.

Authors:  R Simon
Journal:  Ann Intern Med       Date:  1986-09       Impact factor: 25.391

2.  Antibiotic susceptibility testing by a standardized single disk method.

Authors:  A W Bauer; W M Kirby; J C Sherris; M Turck
Journal:  Am J Clin Pathol       Date:  1966-04       Impact factor: 2.493

3.  In vitro activity of WIN 49375 compared with those of other antibiotics in isolates from cancer patients.

Authors:  I Garcia; G P Bodey; V Fainstein; D H Ho; B LeBlanc
Journal:  Antimicrob Agents Chemother       Date:  1984-09       Impact factor: 5.191

4.  In vitro susceptibilities of 393 recent clinical isolates to WIN 49375, cefotaxime, tobramycin, and piperacillin.

Authors:  D J Pohlod; L D Saravolatz
Journal:  Antimicrob Agents Chemother       Date:  1984-03       Impact factor: 5.191

5.  Antibacterial activity of amifloxacin (WIN 49, 375), a new quinolone agent.

Authors:  H C Neu; P Labthavikul
Journal:  Diagn Microbiol Infect Dis       Date:  1985-11       Impact factor: 2.803

6.  The comparative activity of twelve 4-quinolone antimicrobials and sulphadiazine against Neisseria meningitidis.

Authors:  D Felmingham; R A Wall
Journal:  Drugs Exp Clin Res       Date:  1985

7.  Comparative antimicrobial activity of enoxacin, ciprofloxacin, amifloxacin, norfloxacin and ofloxacin against 177 bacterial isolates.

Authors:  C M Bassey; A L Baltch; R P Smith
Journal:  J Antimicrob Chemother       Date:  1986-05       Impact factor: 5.790
  7 in total
  2 in total

Review 1.  Quinolones for uncomplicated acute cystitis in women.

Authors:  V Rafalsky; I Andreeva; E Rjabkova
Journal:  Cochrane Database Syst Rev       Date:  2006-07-19

2.  Comparative, double-blind, prospective, multicenter trial of temafloxacin versus trimethoprim-sulfamethoxazole in uncomplicated urinary tract infections in women.

Authors:  A Iravani
Journal:  Antimicrob Agents Chemother       Date:  1991-09       Impact factor: 5.191
  2 in total

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