Literature DB >> 21881252

Anti-hepatitis B virus and cytotoxic diterpenoids from Isodon lophanthoides var. gerardianus.

Li-bin Yang1, Lin Li, Sheng-xiong Huang, Jian-xin Pu, Yong Zhao, Yun-bao Ma, Ji-jun Chen, Chun-hong Leng, Zheng-ming Tao, Han-dong Sun.   

Abstract

Four new diterpenoides, isolophanthins A-D (1-4) together with seven known abietane diterpenoides (5-11), have been isolated from Isodon lophanthoides var. gerardianus. The new diterpenoides were elucidated by spectroscopic analysis. Some of them showed significant activities against HBsAg and HBeAg of hepatitis B virus in Hep G 2.2.15 cells, as well as the human tumor cell lines, HL-60, A-549, MOLT-4, and BEL-7402.

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Year:  2011        PMID: 21881252     DOI: 10.1248/cpb.59.1102

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  3 in total

1.  Rapid differentiation of Xihuangcao from the three Isodon species by UPLC-ESI-QTOF-MS/MS and chemometrics analysis.

Authors:  Lai Lai Wong; Zhitao Liang; Hubiao Chen; Zhongzhen Zhao
Journal:  Chin Med       Date:  2016-12-15       Impact factor: 5.455

2.  Crystal structure of (4bS,8aR)-1-isopropyl-4b,8,8-trimethyl-7-oxo-4b,7,8,8a,9,10-hexa-hydro-phenanthren-2-yl acetate.

Authors:  Yassine Laamari; Moulay Youssef Ait Itto; Abdelkhalek Riahi; Sylviane Chevreux; Aziz Auhmani; El Mostafa Ketatni
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2018-04-27

3.  Pharmacophore based virtual screening for natural product database revealed possible inhibitors for SARS-COV-2 main protease.

Authors:  Mohamed K El-Ashrey; Riham O Bakr; Marwa A A Fayed; Rana H Refaey; Yassin M Nissan
Journal:  Virology       Date:  2022-03-22       Impact factor: 3.513

  3 in total

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