Literature DB >> 2187794

Biological false positive serological tests for syphilis in the Jamaican population.

M F Smikle1, O B James, P Prabhakar.   

Abstract

A total of 19,067 sera were screened for biological false positive (BFP) reactivity by the Venereal Disease Research Laboratory (VDRL) test. Sera which were reactive in the VDRL test were confirmed by the fluorescent treponemal antibody absorption (FTA-ABS) test. BFP reactions were detected in 0.59% of the general population, 0.72% of pregnant women and 11.8% of patients with systemic lupus erythematosus (SLE). The rate of BFP reactors among pregnant women did not differ significantly from the general population. The female to male ratio of BFP in the general population was 2:1 whilst that in the group of patients with SLE was 8:1. The overall seroprevalence of syphilis was 2.2%.

Entities:  

Keywords:  Americas; Caribbean; Delivery Of Health Care; Demographic Factors; Developing Countries; Diseases; Examinations And Diagnoses; Health; Health Services; Infections; Jamaica; Laboratory Examinations And Diagnoses; Laboratory Procedures; Maternal Health Services; Maternal-child Health Services; Migrants; Migration; North America; Population; Population Dynamics; Pregnancy; Prenatal Care; Primary Health Care; Reproduction; Reproductive Tract Infections; Research Report; Screening; Sexually Transmitted Diseases; Syphilis; Systemic Lupus Erythematosus

Mesh:

Year:  1990        PMID: 2187794      PMCID: PMC1194464          DOI: 10.1136/sti.66.2.76

Source DB:  PubMed          Journal:  Genitourin Med        ISSN: 0266-4348


  17 in total

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Journal:  Arch Dermatol       Date:  1980-01

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Journal:  Br J Vener Dis       Date:  1980-02

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Journal:  Br J Vener Dis       Date:  1980-02

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Journal:  West Indian Med J       Date:  1978-03       Impact factor: 0.171

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Authors:  P Diggory
Journal:  Br J Vener Dis       Date:  1983-02
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  10 in total

1.  The decentralization of syphilis screening for improved care in Jamaican public clinics. Collaborative Working Group on Decentralized Syphilis Screening.

Authors:  F M Behets; A Brathwaite; L Bennett; K G Douglas; G A Dallabetta; J P Figueroa
Journal:  Am J Public Health       Date:  1997-06       Impact factor: 9.308

2.  Performance of routine syphilis serology in the Ethiopian cohort on HIV/AIDS.

Authors:  J W Dorigo-Zetsma; D Belewu; H Meless; E Sanders; R A Coutinho; A Schaap; D Wolday
Journal:  Sex Transm Infect       Date:  2004-04       Impact factor: 3.519

3.  Frequency and Characteristics of Biological False-Positive Test Results for Syphilis Reported in Florida and New York City, USA, 2013 to 2017.

Authors:  James Matthias; Ellen J Klingler; Julia A Schillinger; Gayle Keller; Craig Wilson; Thomas A Peterman
Journal:  J Clin Microbiol       Date:  2019-10-23       Impact factor: 5.948

4.  Seroprevalence of syphilis by VDRL test and biological false positive reactions in different patient populations: Is it alarming? Our experience from a tertiary care center in India.

Authors:  Vrushali Vishwas Patwardhan; Sonali Bhattar; Preena Bhalla; Deepti Rawat
Journal:  Indian J Sex Transm Dis AIDS       Date:  2016-11-17

5.  Modelling the cost-effectiveness of introducing rapid syphilis tests into an antenatal syphilis screening programme in Mwanza, Tanzania.

Authors:  P Vickerman; R W Peeling; F Terris-Prestholt; J Changalucha; D Mabey; D Watson-Jones; C Watts
Journal:  Sex Transm Infect       Date:  2006-12       Impact factor: 3.519

6.  Changing trends in acquired syphilis at a Tertiary Care Center of North India.

Authors:  Parmil K Nishal; Anu Kapoor; Vijay K Jain; Surabhi Dayal; Kamal Aggarwal
Journal:  Indian J Sex Transm Dis AIDS       Date:  2015 Jul-Dec

7.  Syphilis Laboratory Guidelines: Performance Characteristics of Nontreponemal Antibody Tests.

Authors:  Susan Tuddenham; Samantha S Katz; Khalil G Ghanem
Journal:  Clin Infect Dis       Date:  2020-06-24       Impact factor: 9.079

8.  Comparison of 17 serological treponemal and nontreponemal assays for syphilis: A retrospective cohort study.

Authors:  Itsuko Sato; Yuji Nakamachi; Goh Ohji; Yoshihiko Yano; Jun Saegusa
Journal:  Pract Lab Med       Date:  2022-09-29

9.  Evaluation of the usefulness of Treponema pallidum hemagglutination test in the diagnosis of syphilis in weak reactive Venereal Disease Research Laboratory sera.

Authors:  Manju Bala; Aman Toor; Meenakshi Malhotra; Monika Kakran; Sumathi Muralidhar; V Ramesh
Journal:  Indian J Sex Transm Dis AIDS       Date:  2012-07

10.  Syphilitic Reinfections During the Same Pregnancy-Florida, 2018.

Authors:  James Matthias; Ruth Sanon; Virginia B Bowen; Emma C Spencer; Thomas A Peterman
Journal:  Sex Transm Dis       Date:  2021-05-01       Impact factor: 3.868

  10 in total

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