| Literature DB >> 2187534 |
R P Martin1, A P Sibler, C W Gehrke, K Kuo, C G Edmonds, J A McCloskey, G Dirheimer.
Abstract
The modified nucleoside (U*) present in the wobble position of Saccharomyces cerevisiae mitochondrial tRNA(Leu) and tRNA(Trp) was isolated by thin-layer chromatography and HPLC. Its chromatographic, UV spectral, and mass spectrometric properties were shown to be identical with those of 5- [[(carboxymethyl)amino]methyl]uridine (cmnm5U). This nucleoside found in yeast mitochondrial tRNAs reading two-codon families ending in a purine permits the selective recognition of A and G in the third codon position.Entities:
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Year: 1990 PMID: 2187534 DOI: 10.1021/bi00456a016
Source DB: PubMed Journal: Biochemistry ISSN: 0006-2960 Impact factor: 3.162