| Literature DB >> 218609 |
M F Holick, N M Richtand, S C McNeill, S A Holick, J E Frommer, J W Henley, J T Potts.
Abstract
The process of the photolytic activation of vitamin D precursor(s) in the skin has been elucidated by a detailed analysis of the products formed after ultraviolet light exposure. The photolytic product isolated from the skin of rats exposed to ultraviolet irradiation was identified as previtamin D3 by several criteria including its (a) characteristic ultraviolet absorption spectrum, (b) mass spectrum, and (c) thermal isomerization to vitamin D3, which itself was identified also by mass spectroscopy. Vitamin D3 per se was not formed by ultraviolet irradiation--vitamin D3 arises exclusively from the thermal conversion of previtamin D3. Detectable amounts of lumisterol3 or tachysterol3 were not seen.Entities:
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Year: 1979 PMID： 218609 DOI： 10.1021/bi00573a011
Source DB: PubMed Journal: Biochemistry ISSN： 0006-2960 Impact factor: 3.162