Literature DB >> 21859578

Design aspects of focal beams from high-intensity arrays.

Douglas Stephens1, Dustin Kruse, Shengping Qin, Katherine Ferrara.   

Abstract

As the applications of ultrasonic thermal therapies expand, the design of the high-intensity array must address both the energy delivery of the main beam and the character and relevance of off-target beam energy. We simulate the acoustic field performance of a selected set of circular arrays organized by array format, including flat versus curved arrays, periodic versus random arrays, and center void diameter variations. Performance metrics are based on the -3-dB focal main lobe (FML) positioning range, axial grating lobe (AGL) temperatures, and side lobe levels. Using finite-element analysis, we evaluate the relative heating of the FML and the AGLs. All arrays have a maximum diameter of 100λ, with element count ranging from 64 to 1024 and continuous wave frequency of 1.5 MHz. First, we show that a 50% spherical annulus produces focus beam side lobes which decay as a function of lateral distance at nearly 87% of the exponential rate of a full aperture. Second, for the arrays studied, the efficiency of power delivery over the -3-dB focus positioning range for spherical arrays is at least 2-fold greater than for flat arrays; the 256-element case shows a 5-fold advantage for the spherical array. Third, AGL heating can be significant as the focal target is moved to its distal half-intensity depth from the natural focus. Increasing the element count of a randomized array to 256 elements decreases the AGL-to-FML heating ratio to 0.12 at the distal half-intensity depth. Further increases in element count yield modest improvements. A 49% improvement in the AGL-to-peak heating ratio is predicted by using the Sumanaweera spiral element pattern with randomization.

Entities:  

Mesh:

Year:  2011        PMID: 21859578      PMCID: PMC3174850          DOI: 10.1109/TUFFC.2011.1986

Source DB:  PubMed          Journal:  IEEE Trans Ultrason Ferroelectr Freq Control        ISSN: 0885-3010            Impact factor:   2.725


  35 in total

1.  Investigation of cross-coupling in 1-3 piezocomposite arrays.

Authors:  D Certon; N Felix; E Lacaze; F Teston; F Patat
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2001-01       Impact factor: 2.725

2.  FDTD simulation of finite-amplitude pressure and temperature fields for biomedical ultrasound.

Authors:  I M Hallaj; R O Cleveland
Journal:  J Acoust Soc Am       Date:  1999-05       Impact factor: 1.840

3.  Perspectives in clinical uses of high-intensity focused ultrasound.

Authors:  G T Clement
Journal:  Ultrasonics       Date:  2004-08       Impact factor: 2.890

4.  Gaussian representation of high-intensity focused ultrasound beams.

Authors:  Joshua E Soneson; Matthew R Myers
Journal:  J Acoust Soc Am       Date:  2007-11       Impact factor: 1.840

5.  Optimization of ultrasound array designs for high intensity focused treatment of prostate cancer and benign prostatic hyperplasia.

Authors:  Khaldon Lweesy; Luay Fraiwan; Osama Al-Bataineh; Naser Hamdi; Hartmut Dickhaus
Journal:  Med Biol Eng Comput       Date:  2009-03-27       Impact factor: 2.602

6.  A random phased array device for delivery of high intensity focused ultrasound.

Authors:  J W Hand; A Shaw; N Sadhoo; S Rajagopal; R J Dickinson; L R Gavrilov
Journal:  Phys Med Biol       Date:  2009-09-01       Impact factor: 3.609

7.  Analytical and numerical calculations of optimum design frequency for focused ultrasound therapy and acoustic radiation force.

Authors:  A Sanlı Ergün
Journal:  Ultrasonics       Date:  2011-03-23       Impact factor: 2.890

Review 8.  Analytical modelling of ultrasonically induced tissue heating.

Authors:  F L Lizzi; M Ostromogilsky
Journal:  Ultrasound Med Biol       Date:  1987-10       Impact factor: 2.998

9.  Focused ultrasound treatment of uterine fibroid tumors: safety and feasibility of a noninvasive thermoablative technique.

Authors:  Elizabeth A Stewart; Wladyslaw M W Gedroyc; Clare M C Tempany; Bradley J Quade; Yael Inbar; Tilman Ehrenstein; Asher Shushan; Jonathan T Hindley; Robert D Goldin; Matthias David; Miri Sklair; Jaron Rabinovici
Journal:  Am J Obstet Gynecol       Date:  2003-07       Impact factor: 8.661

10.  A NEW METHOD FOR THE GENERATION AND USE OF FOCUSED ULTRASOUND IN EXPERIMENTAL BIOLOGY.

Authors:  J G Lynn; R L Zwemer; A J Chick; A E Miller
Journal:  J Gen Physiol       Date:  1942-11-20       Impact factor: 4.086

View more
  5 in total

1.  Development of a spherically focused phased array transducer for ultrasonic image-guided hyperthermia.

Authors:  Jingfei Liu; Josquin Foiret; Douglas N Stephens; Olivier Le Baron; Katherine W Ferrara
Journal:  Phys Med Biol       Date:  2016-06-29       Impact factor: 3.609

2.  Simulation of nonlinear trans-skull focusing and formation of shocks in brain using a fully populated ultrasound array with aberration correction.

Authors:  Pavel B Rosnitskiy; Petr V Yuldashev; Oleg A Sapozhnikov; Leonid R Gavrilov; Vera A Khokhlova
Journal:  J Acoust Soc Am       Date:  2019-09       Impact factor: 1.840

3.  In situ bone tissue engineering via ultrasound-mediated gene delivery to endogenous progenitor cells in mini-pigs.

Authors:  Maxim Bez; Dmitriy Sheyn; Wafa Tawackoli; Pablo Avalos; Galina Shapiro; Joseph C Giaconi; Xiaoyu Da; Shiran Ben David; Jayne Gavrity; Hani A Awad; Hyun W Bae; Eric J Ley; Thomas J Kremen; Zulma Gazit; Katherine W Ferrara; Gadi Pelled; Dan Gazit
Journal:  Sci Transl Med       Date:  2017-05-17       Impact factor: 17.956

4.  Flexible integration of high-imaging-resolution and high-power arrays for ultrasound-induced thermal strain imaging (US-TSI).

Authors:  Douglas N Stephens; Ahmed M Mahmoud; Xuan Ding; Steven Lucero; Debaditya Dutta; Francois T H Yu; Xucai Chen; Kang Kim
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2013-12       Impact factor: 2.725

5.  A Prototype Therapy System for Boiling Histotripsy in Abdominal Targets Based on a 256-Element Spiral Array.

Authors:  Christopher R Bawiec; Tatiana D Khokhlova; Oleg A Sapozhnikov; Pavel B Rosnitskiy; Bryan W Cunitz; Mohamed A Ghanem; Christopher Hunter; Wayne Kreider; George R Schade; Petr V Yuldashev; Vera A Khokhlova
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2021-04-26       Impact factor: 2.725

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.