Literature DB >> 21857348

A comparison of radical vaginal hysterectomy combined with extraperitoneal or laparoscopic pelvic lymphadenectomy in the treatment of cervical cancer.

Diego Maestri1, Rosilene Jara Reis, Omar Moreira Bacha, Betânia Müller, Oly Campos Corleta.   

Abstract

BACKGROUND: The use of radical vaginal hysterectomy in the treatment of cervical cancer is associated with lower morbidity and a similar cure rate when compared with the abdominal approach. The present study reports a case series of radical vaginal hysterectomy followed by extraperitoneal (Mitra) or video-laparoscopic (VLP) lymphadenectomy, with comparison of the 2 techniques.
METHODS: Twenty-five patients with cervical carcinoma (stages IA1 to IIA) were submitted to radical vaginal hysterectomy and extraperitoneal or laparoscopic lymphadenectomy.
RESULTS: The Mitra technique was used in 17 cases, and VLP was used in 8. Seventeen patients presented minor postoperative complications. The number of resected lymph nodes was similar with both techniques (median of 14 with VLP vs. 21 with Mitra) (P = 0.215). The duration of surgery in the VLP group (mean, 339 minutes) was shorter than that of the Mitra group (mean, 421 minutes) (P = 0.015).
CONCLUSIONS: The results obtained with both techniques are similar to those reported in the literature. The duration of extraperitoneal lymphadenectomy was longer than that of VLP lymphadenectomy. There were no differences between the 2 techniques concerning the number of resected lymph nodes and hospital stay.

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Mesh:

Year:  2012        PMID: 21857348     DOI: 10.1111/IGC.0b013e3181f93516

Source DB:  PubMed          Journal:  Int J Gynecol Cancer        ISSN: 1048-891X            Impact factor:   3.437


  5 in total

1.  Laparoscopic surgery inhibits the proliferation and metastasis of cervical cancer cells.

Authors:  Shouguo Huang; Jie Qin; Jin Chen; Hong Cheng; Qiu Meng; Jing Zhang; Haiyan Wang; Huaying Li
Journal:  Int J Clin Exp Med       Date:  2015-09-15

Review 2.  Radical Hysterectomy After the LACC Trial: Back to Radical Vaginal Surgery.

Authors:  Denis Querleu; Delphine Hudry; Fabrice Narducci; Agnieszka Rychlik
Journal:  Curr Treat Options Oncol       Date:  2022-02-23

3.  Valproic acid inhibits the angiogenic potential of cervical cancer cells via HIF-1α/VEGF signals.

Authors:  Y Zhao; W You; J Zheng; Y Chi; W Tang; R Du
Journal:  Clin Transl Oncol       Date:  2016-03-04       Impact factor: 3.405

4.  miR-16-5p/PDK4-Mediated Metabolic Reprogramming Is Involved in Chemoresistance of Cervical Cancer.

Authors:  Zhao Zhao; Mei Ji; Qianqing Wang; Nannan He; Yue Li
Journal:  Mol Ther Oncolytics       Date:  2020-05-23       Impact factor: 7.200

5.  Effects of propofol and sevoflurane on perioperative immune response in patients undergoing laparoscopic radical hysterectomy for cervical cancer.

Authors:  Songtao Liu; Xinyu Gu; Lijiao Zhu; Guannan Wu; Hai Zhou; Yan Song; Congyou Wu
Journal:  Medicine (Baltimore)       Date:  2016-12       Impact factor: 1.817

  5 in total

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