Literature DB >> 21853231

Femtosecond laser treatment of the crystalline lens: a 1-year study of possible cataractogenesis in minipigs.

Roland Ackermann1, Kathleen S Kunert, Robert Kammel, Sabine Bischoff, Stephanie C Bühren, Harald Schubert, Marcus Blum, Stefan Nolte.   

Abstract

BACKGROUND: To investigate the long-term stability and possible cataractogenesis after femtosecond laser treatment of the crystalline lens.
METHODS: The crystalline lenses of ten Göttingen minipigs® underwent femtosecond laser treatment. During a subsequent 1-year follow-up, the pigs were monitored by means of slit-lamp examination of the anterior segment and Scheimpflug imaging of the lens.
RESULTS: No laser-induced cataractogenesis was observed during the 1-year follow-up. The laser pattern showed a stable appearance under all examination devices.
CONCLUSION: Femtosecond laser treatment seems to be no trigger for cataract formation. Moreover, the long-term stability of the laser pattern makes it suitable for applications such as presbyopia treatment.

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Year:  2011        PMID: 21853231     DOI: 10.1007/s00417-011-1772-z

Source DB:  PubMed          Journal:  Graefes Arch Clin Exp Ophthalmol        ISSN: 0721-832X            Impact factor:   3.117


  12 in total

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2.  Modeling the growth of the Goettingen minipig.

Authors:  F Köhn; A R Sharifi; H Simianer
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3.  First safety study of femtosecond laser photodisruption in animal lenses: tissue morphology and cataractogenesis.

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5.  Effect of a suction device for femtosecond laser on anterior chamber depth and crystalline lens position measured by OCT.

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8.  Cataract induction in rabbits with the Nd-YAG laser.

Authors:  G Cangelosi; M B McDonald; K S Morgan
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9.  Focal laser photophacoablation of normal and cataractous lenses in rabbits: preliminary report.

Authors:  A Gwon; F Fankhauser; C Puliafito; L Gruber; M Berns
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Authors:  J Keenan; D F Orr; B K Pierscionek
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  4 in total

1.  Analysis of optical side-effects of fs-laser therapy in human presbyopic lens simulated with modified contact lenses.

Authors:  Monika Peter; Robert Kammel; Roland Ackermann; Stefan Schramm; Bernd-Ulrich Seifert; Katharina Frey; Marcus Blum; Stefan Nolte; Kathleen S Kunert
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2012-02-29       Impact factor: 3.117

Review 2.  Femtosecond laser in refractive and cataract surgeries.

Authors:  Han-Han Liu; Ying Hu; Hong-Ping Cui
Journal:  Int J Ophthalmol       Date:  2015-04-18       Impact factor: 1.779

3.  Ultrashort-pulse lasers treating the crystalline lens: will they cause vision-threatening cataract? (An American Ophthalmological Society thesis).

Authors:  Ronald R Krueger; Harvey Uy; Jared McDonald; Keith Edwards
Journal:  Trans Am Ophthalmol Soc       Date:  2012-12

4.  Optical side-effects of fs-laser treatment in refractive surgery investigated by means of a model eye.

Authors:  Roland Ackermann; Robert Kammel; Marina Merker; Andreas Kamm; Andreas Tünnermann; Stefan Nolte
Journal:  Biomed Opt Express       Date:  2013-01-10       Impact factor: 3.732

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