Literature DB >> 21852764

Linezolid and lactic acidosis: a role for lactate monitoring with long-term linezolid use in children.

Erik Su1, Kelli Crowley, Joseph A Carcillo, Marian G Michaels.   

Abstract

Linezolid administration has been associated with lactic acidosis in adults; however, the same phenomenon has not been reported in children. Mitochondrial protein synthesis inhibition is a demonstrated mechanism for toxicity, which therefore may manifest as lactic acidosis. Three cases of linezolid-associated lactic acidosis in children are reported to reinforce the need for pediatric caregivers to be vigilant of this potential side effect.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21852764      PMCID： PMC3158859          DOI： 10.1097/INF.0b013e3182186035

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  10 in total

1.  Linezolid-induced lactic acidosis.

Authors:  Aaron A Apodaca; Robert M Rakita
Journal:  N Engl J Med       Date:  2003-01-02       Impact factor: 91.245

2.  Mitochondrial toxicity associated with linezolid.

Authors:  Alex Soriano; Oscar Miró; Josep Mensa
Journal:  N Engl J Med       Date:  2005-11-24       Impact factor: 91.245

3.  Hyperlactacidemia potentially due to linezolid overexposure in a liver transplant recipient.

Authors:  Federico Pea; Luigia Scudeller; Manuela Lugano; Umberto Baccarani; Federica Pavan; Marcello Tavio; Mario Furlanut; Giorgio Della Rocca; Fabrizio Bresadola; Pierluigi Viale
Journal:  Clin Infect Dis       Date:  2006-02-01       Impact factor: 9.079

4.  Does linezolid inhibit its own metabolism? Population pharmacokinetics as a tool to explain the observed nonlinearity in both healthy volunteers and septic patients.

Authors:  N Plock; C Buerger; C Joukhadar; S Kljucar; C Kloft
Journal:  Drug Metab Dispos       Date:  2007-07-16       Impact factor: 3.922

5.  Reversible inhibition of mitochondrial protein synthesis during linezolid-related hyperlactatemia.

Authors:  Glòria Garrabou; Alejandro Soriano; Sònia López; Jordi P Guallar; Marta Giralt; Francesc Villarroya; Jose A Martínez; Jordi Casademont; Francesc Cardellach; Josep Mensa; Oscar Miró
Journal:  Antimicrob Agents Chemother       Date:  2006-12-28       Impact factor: 5.191

6.  Higher linezolid exposure and higher frequency of thrombocytopenia in patients with renal dysfunction.

Authors:  Kazuaki Matsumoto; Ayumi Takeshita; Kazuro Ikawa; Akari Shigemi; Keiko Yaji; Yoshihiro Shimodozono; Norifumi Morikawa; Yasuo Takeda; Katsushi Yamada
Journal:  Int J Antimicrob Agents       Date:  2010-04-13       Impact factor: 5.283

7.  Linezolid-induced inhibition of mitochondrial protein synthesis.

Authors:  An S De Vriese; Rudy Van Coster; Joel Smet; Sara Seneca; Andrew Lovering; Lindsey L Van Haute; Ludo J Vanopdenbosch; Jean-Jacques Martin; Chantal Ceuterick-de Groote; Stefaan Vandecasteele; Johan R Boelaert
Journal:  Clin Infect Dis       Date:  2006-03-13       Impact factor: 9.079

8.  Does linezolid cause lactic acidosis by inhibiting mitochondrial protein synthesis?

Authors:  Lluis Palenzuela; Noah M Hahn; Robert P Nelson; Janet N Arno; Carol Schobert; Robert Bethel; Lisa A Ostrowski; Manjuli R Sharma; Partha P Datta; Rajendra K Agrawal; Jennifer E Schwartz; Michio Hirano
Journal:  Clin Infect Dis       Date:  2005-05-03       Impact factor: 9.079

9.  Chronic liver disease increases the risk of linezolid-related thrombocytopenia in methicillin-resistant Staphylococcus aureus-infected patients after digestive surgery.

Authors:  Shin-ichi Ikuta; Kiyoko Tanimura; Chiaki Yasui; Tsukasa Aihara; Hidenori Yoshie; Hiroya Iida; Naohito Beppu; Ami Kurimoto; Hidenori Yanagi; Masao Mitsunobu; Naoki Yamanaka
Journal:  J Infect Chemother       Date:  2010-12-16       Impact factor: 2.211

Review 10.  Linezolid-associated peripheral and optic neuropathy, lactic acidosis, and serotonin syndrome.

Authors:  Masashi Narita; Brian T Tsuji; Victor L Yu
Journal:  Pharmacotherapy       Date:  2007-08       Impact factor: 4.705
  10 in total
  14 in total

1.  Pharmacokinetics of linezolid treatment using intravenous and oral administrations in extremely premature infants.

Authors:  Mélanie Sicard; Elise Launay; Jocelyne Caillon; Cédric Jacqueline; Arnaud Legrand; Guillaume Deslandes; Dominique Navas; Jean-Christophe Rozé; Christèle Gras-Le Guen
Journal:  Eur J Clin Pharmacol       Date:  2015-03-06       Impact factor: 2.953

2.  A triad of linezolid toxicity: hypoglycemia, lactic acidosis, and acute pancreatitis.

Authors:  P Connor Johnson; Muthiah Vaduganathan; Kristy M Phillips; Walter J O'Donnell
Journal:  Proc (Bayl Univ Med Cent)       Date:  2015-10

3.  Pharmacokinetics of tedizolid in subjects with renal or hepatic impairment.

Authors:  S Flanagan; S L Minassian; D Morris; R Ponnuraj; T C Marbury; H W Alcorn; E Fang; P Prokocimer
Journal:  Antimicrob Agents Chemother       Date:  2014-08-18       Impact factor: 5.191

Review 4.  Drug-induced acid-base disorders.

Authors:  Daniel Kitterer; Matthias Schwab; M Dominik Alscher; Niko Braun; Joerg Latus
Journal:  Pediatr Nephrol       Date:  2014-11-05       Impact factor: 3.714

Review 5.  Safety and tolerability profile of second-line anti-tuberculosis medications.

Authors:  Geetha Ramachandran; Soumya Swaminathan
Journal:  Drug Saf       Date:  2015-03       Impact factor: 5.606

6.  Influence of Mitochondrial Genetics on the Mitochondrial Toxicity of Linezolid in Blood Cells and Skin Nerve Fibers.

Authors:  G Garrabou; À Soriano; T Pinós; J Casanova-Mollà; D Pacheu-Grau; C Morén; E García-Arumí; M Morales; E Ruiz-Pesini; M Catalán-Garcia; J C Milisenda; E Lozano; A L Andreu; J Montoya; J Mensa; F Cardellach
Journal:  Antimicrob Agents Chemother       Date:  2017-08-24       Impact factor: 5.191

7.  Clinical update on linezolid in the treatment of Gram-positive bacterial infections.

Authors:  Sally Ager; Kate Gould
Journal:  Infect Drug Resist       Date:  2012-06-25       Impact factor: 4.003

8.  Lactic Acidosis Induced by Linezolid Mimics Symptoms of an Acute Intracranial Bleed: A Case Report and Literature Review.

Authors:  Nichole Suzzanne Zuccarini; Tariq Yousuf; Daniel Wozniczka; Anis Abdul Rauf
Journal:  J Clin Med Res       Date:  2016-08-30

9.  Double Peripheral Venous and Arterial Cannulation for Extracorporeal Membrane Oxygenation in Combined Septic and Cardiogenic Shock.

Authors:  Markus Kredel; Steffen Kunzmann; Paul-Gerhardt Schlegel; Matthias Wölfl; Peter Nordbeck; Christoph Bühler; Christopher Lotz; Philipp M Lepper; Johannes Wirbelauer; Norbert Roewer; Ralf M Muellenbach
Journal:  Am J Case Rep       Date:  2017-06-28

Review 10.  Nocardiosis in transplant recipients.

Authors:  D Lebeaux; E Morelon; F Suarez; F Lanternier; A Scemla; P Frange; J-L Mainardi; M Lecuit; O Lortholary
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2013-11-23       Impact factor: 5.103
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.