Literature DB >> 21852149

Epicardial adipose tissue: emerging physiological, pathophysiological and clinical features.

Gianluca Iacobellis1, Antonio C Bianco.   

Abstract

Epicardial adipose tissue is an unusual visceral fat depot with anatomical and functional contiguity to the myocardium and coronary arteries. Under physiological conditions, epicardial adipose tissue displays biochemical, mechanical and thermogenic cardioprotective properties. Under pathological circumstances, epicardial fat can locally affect the heart and coronary arteries through vasocrine or paracrine secretion of proinflammatory cytokines. What influences this equilibrium remains unclear. Improved local vascularization, weight loss, and targeted pharmaceutical interventions could help to return epicardial fat to its physiological role. This review focuses on the emerging physiological and pathophysiological aspects of the epicardial fat and its numerous and innovative clinical applications. Particular emphasis is placed on the paracrine/endocrine properties of epicardial fat and its role in the development and progression of atherosclerosis.
Copyright © 2011 Elsevier Ltd. All rights reserved.

Entities:  

Mesh：

Year:  2011        PMID： 21852149      PMCID： PMC4978122          DOI： 10.1016/j.tem.2011.07.003

Source DB:  PubMed          Journal:  Trends Endocrinol Metab        ISSN： 1043-2760            Impact factor:   12.015


  87 in total

1.  Relation between epicardial adipose tissue and left ventricular mass.

Authors:  Gianluca Iacobellis; Maria Cristina Ribaudo; Alessandra Zappaterreno; Concetta Valeria Iannucci; Frida Leonetti
Journal:  Am J Cardiol       Date:  2004-10-15       Impact factor: 2.778

2.  Epicardial and pericardial fat: close, but very different.

Authors:  Gianluca Iacobellis
Journal:  Obesity (Silver Spring)       Date:  2009-04       Impact factor: 5.002

Review 3.  Echocardiographic epicardial fat: a review of research and clinical applications.

Authors:  Gianluca Iacobellis; Howard J Willens
Journal:  J Am Soc Echocardiogr       Date:  2009-12       Impact factor: 5.251

4.  Uncoupling protein-1 and related messenger ribonucleic acids in human epicardial and other adipose tissues: epicardial fat functioning as brown fat.

Authors:  Harold S Sacks; John N Fain; Ben Holman; Paramjeet Cheema; Aron Chary; Frank Parks; James Karas; Robert Optican; Suleiman W Bahouth; Edward Garrett; Rodney Y Wolf; Russell A Carter; Todd Robbins; David Wolford; Joseph Samaha
Journal:  J Clin Endocrinol Metab       Date:  2009-06-30       Impact factor: 5.958

Review 5.  Animal models for the atherosclerosis research: a review.

Authors:  Li Xiangdong; Liu Yuanwu; Zhang Hua; Ren Liming; Li Qiuyan; Li Ning
Journal:  Protein Cell       Date:  2011-04-06       Impact factor: 14.870

6.  Adipose tissue in the mammalian heart and pericardium: structure, foetal development and biochemical properties.

Authors:  J M Marchington; C A Mattacks; C M Pond
Journal:  Comp Biochem Physiol B       Date:  1989

7.  Adiponectin expression in human epicardial adipose tissue in vivo is lower in patients with coronary artery disease.

Authors:  Gianluca Iacobellis; Daniela Pistilli; Marco Gucciardo; Frida Leonetti; Fabio Miraldi; Gianluca Brancaccio; Pietro Gallo; Cira Rosaria Tiziana di Gioia
Journal:  Cytokine       Date:  2005-03-21       Impact factor: 3.861

8.  Expression of adrenomedullin in human epicardial adipose tissue: role of coronary status.

Authors:  Alina Silaghi; Vincent Achard; Odile Paulmyer-Lacroix; Traian Scridon; Virginie Tassistro; Ileana Duncea; Karine Clément; Anne Dutour; Michel Grino
Journal:  Am J Physiol Endocrinol Metab       Date:  2007-09-18       Impact factor: 4.310

9.  Cold-activated brown adipose tissue in healthy men.

Authors:  Wouter D van Marken Lichtenbelt; Joost W Vanhommerig; Nanda M Smulders; Jamie M A F L Drossaerts; Gerrit J Kemerink; Nicole D Bouvy; Patrick Schrauwen; G J Jaap Teule
Journal:  N Engl J Med       Date:  2009-04-09       Impact factor: 91.245

10.  Presence of fatty-acid-binding protein 4 expression in human epicardial adipose tissue in metabolic syndrome.

Authors:  Burcak Vural; Fatmahan Atalar; Cavlan Ciftci; Ayse Demirkan; Belgin Susleyici-Duman; Demet Gunay; Belhhan Akpinar; Ertan Sagbas; Ugur Ozbek; Ahmet Sevim Buyukdevrim
Journal:  Cardiovasc Pathol       Date:  2008-04-15       Impact factor: 2.185
View more
  138 in total

1.  Relationship between epicardial adipose tissue thickness and early impairment of left ventricular systolic function in patients with preserved ejection fraction.

Authors:  Keiko Watanabe; Tomonori Kishino; Junko Sano; Toshiyuki Ariga; Shuhei Okuyama; Hideaki Mori; Satsuki Matsushima; Kouki Ohtsuka; Hiroaki Ohnishi; Takashi Watanabe
Journal:  Heart Vessels       Date:  2015-02-27       Impact factor: 2.037

Review 2.  Epicardial adipose tissue in endocrine and metabolic diseases.

Authors:  Gianluca Iacobellis
Journal:  Endocrine       Date:  2013-11-23       Impact factor: 3.633

3.  Perivascular adipose tissue of the descending thoracic aorta is associated with systemic lupus erythematosus and vascular calcification in women.

Authors:  Kelly J Shields; Emma Barinas-Mitchell; Matthew R Gingo; Ping Tepper; Bret H Goodpaster; Amy H Kao; Susan Manzi; Kim Sutton-Tyrrell
Journal:  Atherosclerosis       Date:  2013-09-11       Impact factor: 5.162

Review 4.  Cardiac adipose tissue and its relationship to diabetes mellitus and cardiovascular disease.

Authors:  Adam M Noyes; Kirandeep Dua; Ramprakash Devadoss; Lovely Chhabra
Journal:  World J Diabetes       Date:  2014-12-15

Review 5.  Local and systemic effects of the multifaceted epicardial adipose tissue depot.

Authors:  Gianluca Iacobellis
Journal:  Nat Rev Endocrinol       Date:  2015-04-07       Impact factor: 43.330

Review 6.  Epicardial adipose tissue: far more than a fat depot.

Authors:  Andrew H Talman; Peter J Psaltis; James D Cameron; Ian T Meredith; Sujith K Seneviratne; Dennis T L Wong
Journal:  Cardiovasc Diagn Ther       Date:  2014-12

7.  Localization profiles of natriuretic peptides in hearts of pre-hibernating and hibernating Anatolian ground squirrels (Spermophilus xanthoprymnus).

Authors:  Mustafa Öztop; Mehmet Özbek; Narin Liman; Feyzullah Beyaz; Emel Ergün; Levent Ergün
Journal:  Vet Res Commun       Date:  2019-01-28       Impact factor: 2.459

8.  Epicardial Fat Thickness in Patients with Autosomal Dominant Polycystic Kidney Disease.

Authors:  Antonio Concistrè; Luigi Petramala; Gianmarco Scoccia; Susanna Sciomer; Valeria Bisogni; Vincenza Saracino; Gino Iannucci; Silvia Lai; Daniela Mastroluca; Gianluca Iacobellis; Claudio Letizia
Journal:  Cardiorenal Med       Date:  2018-05-03       Impact factor: 2.041

9.  Adipogenesis and epicardial adipose tissue: a novel fate of the epicardium induced by mesenchymal transformation and PPARγ activation.

Authors:  Yukiko Yamaguchi; Susana Cavallero; Michaela Patterson; Hua Shen; Jian Xu; S Ram Kumar; Henry M Sucov
Journal:  Proc Natl Acad Sci U S A       Date:  2015-02-02       Impact factor: 11.205

Review 10.  Relationship between epicardial adipose tissue volume and atrial fibrillation : A systematic review and meta-analysis.

Authors:  W Zhu; H Zhang; L Guo; K Hong
Journal:  Herz       Date:  2015-12-10       Impact factor: 1.443
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.