Literature DB >> 21850614

[Results of transoral laser resection in T1-2 oropharyngeal, hypopharyngeal and laryngeal carcinomas].

H Iro1, K Mantsopoulos, J Zenk, F Waldfahrer, G Psychogios.   

Abstract

BACKGROUND: Transoral laser microsurgery (TLM) has led to an expansion of the therapeutic modalities for malignomas of head and neck. This study aims to assess the oncologic results and functional outcomes of TLM in early carcinomas. PATIENTS AND METHODS: This is a retrospective study of 947 cases with T1-2 carcinomas primarily managed with laser surgery between 1979 and 2007. All cases were assessed for survival, with respect to location, T and N classification and status of surgical margins. Cases were additionally evaluated for incidence of major complications and retention of laryngeal and pharyngeal function.
RESULTS: Disease specific survival was 78.6% for oropharyngeal, 68.9% for hypopharyngeal, 82.3% for supraglottic und 95.2% for glottis carcinomas. Survival estimates were found to be significantly better for cases without cervical metastasis and with negative surgical margins. A low rate of major complications (4.7%) were noted. 1% of the patients had a permanent dysfunction of swallowing and 1.1 % needed a permanent tracheostomy.
CONCLUSION: Laser surgery appears to be a very effective management modality for small carcinomas of the head and neck as long as clear surgical margins can be achieved. This technique offers acceptable oncologic results with a low incidence of complications and satisfactory retention of function.

Entities:  

Mesh:

Year:  2011        PMID: 21850614     DOI: 10.1055/s-0031-1283154

Source DB:  PubMed          Journal:  Laryngorhinootologie        ISSN: 0935-8943            Impact factor:   1.057


  13 in total

1.  [The value of supracricoid partial laryngectomy in moderately advanced laryngeal cancer (T3-T4a)].

Authors:  U Schroeder; B Wollenberg; K L Bruchhage
Journal:  HNO       Date:  2015-11       Impact factor: 1.284

2.  [Recent advances in the treatment of laryngeal and hypopharyngeal carcinoma].

Authors:  H E Eckel
Journal:  HNO       Date:  2012-01       Impact factor: 1.284

3.  Assessing quality of life in patients after partial laryngectomy.

Authors:  F Hebel; K Mantsopoulos; C Bohr
Journal:  Hippokratia       Date:  2014-04       Impact factor: 0.471

4.  Outcome of transoral robotic surgery for stage I-II oropharyngeal cancer.

Authors:  J W L van Loon; L E Smeele; F J M Hilgers; M W M van den Brekel
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-03-08       Impact factor: 2.503

5.  Lymph node ratio as a predictor of outcome in patients with oropharyngeal cancer.

Authors:  Julian Künzel; Georgios Psychogios; Konstantinos Mantsopoulos; Philipp Grundtner; Frank Waldfahrer; Heinrich Iro
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-06-19       Impact factor: 2.503

Review 6.  [Current treatment strategies for papillary thyroid microcarcinoma].

Authors:  J Plzák; J Astl; G Psychogios; J Zenk; P Laštůvka; J Betka
Journal:  HNO       Date:  2013-04       Impact factor: 1.284

7.  Early stage oropharyngeal carcinomas: comparing quality of life for different treatment modalities.

Authors:  Don-Felix Ryzek; Konstantinos Mantsopoulos; Julian Künzel; Philipp Grundtner; Johannes Zenk; Heinrich Iro; Georgios Psychogios
Journal:  Biomed Res Int       Date:  2014-02-25       Impact factor: 3.411

Review 8.  Surgical errors and risks - the head and neck cancer patient.

Authors:  Ulrich Harréus
Journal:  GMS Curr Top Otorhinolaryngol Head Neck Surg       Date:  2013-12-13

9.  Epidemiology and survival of HPV-related tonsillar carcinoma.

Authors:  Georgios Psychogios; Christoph Alexiou; Abba Agaimy; Kathrin Brunner; Michael Koch; Konstantinos Mantsopoulos; Andrea Tomppert; Heinrich Iro
Journal:  Cancer Med       Date:  2014-03-10       Impact factor: 4.452

10.  Transoral treatment strategies for head and neck tumors.

Authors:  Christoph Arens
Journal:  GMS Curr Top Otorhinolaryngol Head Neck Surg       Date:  2012-12-20
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