INTRODUCTION AND HYPOTHESIS: This study aimed to prospectively compare, in terms of efficacy and safety, the tension-free vaginal tape (TVT) and the transobturator vaginal tape inside-out (TVT-O) procedure for stress urinary incontinence. METHODS: A cough stress test was applied to the objective outcomes, while urinary incontinence-specific quality of life questionnaire was applied to the subjective outcomes. A test for non-inferiority was carried out for detecting the success rate between the two groups. RESULTS: The objective success rates were found to be 95.4% (62/65) in the TVT group and 96.4% (108/112) in the TVT-O group. No significant difference was found between these two groups in the success rate by non-inferiority test (P < 0.0005), with significant improvement in quality of life and no significant difference in patient satisfaction rates in the two groups (P > 0.05). CONCLUSIONS: In the study, the TVT-O procedure could be defined to be identical to the TVT approach in success rate by non-inferiority test.
INTRODUCTION AND HYPOTHESIS: This study aimed to prospectively compare, in terms of efficacy and safety, the tension-free vaginal tape (TVT) and the transobturator vaginal tape inside-out (TVT-O) procedure for stress urinary incontinence. METHODS: A cough stress test was applied to the objective outcomes, while urinary incontinence-specific quality of life questionnaire was applied to the subjective outcomes. A test for non-inferiority was carried out for detecting the success rate between the two groups. RESULTS: The objective success rates were found to be 95.4% (62/65) in the TVT group and 96.4% (108/112) in the TVT-O group. No significant difference was found between these two groups in the success rate by non-inferiority test (P < 0.0005), with significant improvement in quality of life and no significant difference in patient satisfaction rates in the two groups (P > 0.05). CONCLUSIONS: In the study, the TVT-O procedure could be defined to be identical to the TVT approach in success rate by non-inferiority test.
Authors: Giovanni A Tommaselli; Costantino Di Carlo; Virginia Gargano; Carmen Formisano; Mariamaddalena Scala; Carmine Nappi Journal: Int Urogynecol J Date: 2010-05-26 Impact factor: 2.894
Authors: Donald M Bushnell; Mona L Martin; Kent H Summers; Jan Svihra; Christos Lionis; Donald L Patrick Journal: Qual Life Res Date: 2005-10 Impact factor: 4.147
Authors: Jerry G Blaivas; Rajveer S Purohit; Matthew S Benedon; Gabriel Mekel; Michael Stern; Mubashir Billah; Kola Olugbade; Robert Bendavid; Vladimir Iakovlev Journal: Nat Rev Urol Date: 2015-08-18 Impact factor: 14.432