Literature DB >> 21848268

Monanchocidins B-E: polycyclic guanidine alkaloids with potent antileukemic activities from the sponge Monanchora pulchra.

Tatyana N Makarieva1, Ksenya M Tabakmaher, Alla G Guzii, Vladimir A Denisenko, Pavel S Dmitrenok, Larisa K Shubina, Alexandra S Kuzmich, Hyi-Seung Lee, Valentin A Stonik.   

Abstract

New unusual polycyclic guanidine alkaloids monanchocidins B-E (2-5) along with monanchocidin A (1), which we recently described, were isolated from the Far-Eastern marine sponge Monanchora pulchra. Their structures were established using spectroscopic data and chemical transformations. Compounds 1-5 show potent cytotoxic activities against HL-60 human leukemia cells with IC50 values of 540, 200, 110, 830, and 650 nM, respectively.

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Year:  2011        PMID： 21848268     DOI： 10.1021/np200452m

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  14 in total

Review 1.  Structure, synthesis and biological properties of the pentacyclic guanidinium alkaloids.

Authors:  Yunlong Shi; Yasamin Moazami; Joshua G Pierce
Journal:  Bioorg Med Chem       Date:  2017-03-12       Impact factor: 3.641

Review 2.  Advancement into the Arctic region for bioactive sponge secondary metabolites.

Authors:  Samuel Abbas; Michelle Kelly; John Bowling; James Sims; Amanda Waters; Mark Hamann
Journal:  Mar Drugs       Date:  2011-11-21       Impact factor: 6.085

Review 3.  The Oxepane Motif in Marine Drugs.

Authors:  Héctor Barbero; Carlos Díez-Poza; Asunción Barbero
Journal:  Mar Drugs       Date:  2017-11-15       Impact factor: 5.118

Review 4.  Batzella, Crambe and Monanchora: Highly Prolific Marine Sponge Genera Yielding Compounds with Potential Applications for Cancer and Other Therapeutic Areas.

Authors:  Amr El-Demerdash; Atanas G Atanasov; Anupam Bishayee; Mamdouh Abdel-Mogib; John N A Hooper; Ali Al-Mourabit
Journal:  Nutrients       Date:  2018-01-02       Impact factor: 5.717

5.  Marine Cyclic Guanidine Alkaloids Monanchomycalin B and Urupocidin A Act as Inhibitors of TRPV1, TRPV2 and TRPV3, but not TRPA1 Receptors.

Authors:  Yuliya Korolkova; Tatyana Makarieva; Kseniya Tabakmakher; Larisa Shubina; Ekaterina Kudryashova; Yaroslav Andreev; Irina Mosharova; Hyi-Seung Lee; Yeon-Ju Lee; Sergey Kozlov
Journal:  Mar Drugs       Date:  2017-03-23       Impact factor: 5.118

6.  New Crambescidin-Type Alkaloids from the Indonesian Marine Sponge Clathria bulbotoxa.

Authors:  Kasmiati Kasmiati; Yukio Yoshioka; Tetsuji Okamoto; Makoto Ojika
Journal:  Mar Drugs       Date:  2018-03-08       Impact factor: 5.118

Review 7.  Marine Invertebrate Metabolites with Anticancer Activities: Solutions to the "Supply Problem".

Authors:  Nelson G M Gomes; Ramesh Dasari; Sunena Chandra; Robert Kiss; Alexander Kornienko
Journal:  Mar Drugs       Date:  2016-05-21       Impact factor: 5.118

Review 8.  Polycyclic Guanidine Alkaloids from Poecilosclerida Marine Sponges.

Authors:  Estelle Sfecci; Thierry Lacour; Philippe Amade; Mohamed Mehiri
Journal:  Mar Drugs       Date:  2016-04-09       Impact factor: 5.118

9.  Guanidine Alkaloids from the Marine Sponge Monanchora pulchra Show Cytotoxic Properties and Prevent EGF-Induced Neoplastic Transformation in Vitro.

Authors:  Sergey A Dyshlovoy; Kseniya M Tabakmakher; Jessica Hauschild; Regina K Shchekaleva; Katharina Otte; Alla G Guzii; Tatyana N Makarieva; Ekaterina K Kudryashova; Sergey N Fedorov; Larisa K Shubina; Carsten Bokemeyer; Friedemann Honecker; Valentin A Stonik; Gunhild von Amsberg
Journal:  Mar Drugs       Date:  2016-07-15       Impact factor: 5.118

10.  Crambescidin 800, Isolated from the Marine Sponge Monanchora viridis, Induces Cell Cycle Arrest and Apoptosis in Triple-Negative Breast Cancer Cells.

Authors:  Sumi Shrestha; Anabel Sorolla; Jane Fromont; Pilar Blancafort; Gavin R Flematti
Journal:  Mar Drugs       Date:  2018-02-08       Impact factor: 5.118
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