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Literature DB >> 21847305

Suicidal ideation and biogenic amines in depression.

V Palaniappan¹, V Ramachandran, O Somasundaram.

Abstract

This report is based on the study of 40 depressives in an attempt to explore the possible association between the suicidal ideas and the biogenic amines. The severity of suicidal ideas was measured on Hamilton Depressive Rating Scale and their amine metabolites were measured (MHFG, HVA and 5 HIAA) in urine and C.S.F. It was observed that the level of 5 HIAA, and Serotonin (5 HT) was more related to suicidal ideas and was inversely related. The probable associations between these are discussed.

Entities: Chemical Disease

Year: 1983 PMID： 21847305 PMCID： PMC3012301

Source DB: PubMed Journal: Indian J Psychiatry ISSN： 0019-5545 Impact factor: 1.759

16 in total

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Authors: J R CROUT; A SJOERDSMA
Journal: N Engl J Med Date: 1959-07-02 Impact factor: 91.245

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Journal: J Neurol Neurosurg Psychiatry Date: 1960-02 Impact factor: 10.154

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Authors: H M Van Praag
Journal: Neuropsychobiology Date: 1977 Impact factor: 2.328

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Authors: J W Maas; J A Fawcett; H Dekirmenjian
Journal: Arch Gen Psychiatry Date: 1972-03

5. Effect of L-tryptophan on brain serotonin metabolism in depressed patients.

Authors: D L Dunner; F K Goodwin
Journal: Arch Gen Psychiatry Date: 1972-04

6. Noradrenaline, 5-hydroxytryptamine, and 5-hydroxyindoleacetic acid in hindbrains of suicidal patients.

Authors: H R Bourne; W E Bunney; R W Colburn; J M Davis; J N Davis; D M Shaw; A J Coppen
Journal: Lancet Date: 1968-10-12 Impact factor: 79.321

7. 5-hydroxytryptamine, noradrenaline, and dopamine in brainstem, hypothalamus, and caudate nucleus of controls and of patients committing suicide by coal-gas poisoning.

Authors: C M Pare; D P Yeung; K Price; R S Stacey
Journal: Lancet Date: 1969-07-19 Impact factor: 79.321

8. Serotonin and 5-hydroxyindoleacetic acid in discrete areas of the brainstem of suicide victims and control patients.

Authors: K G Lloyd; I J Farley; J H Deck; O Hornykiewicz
Journal: Adv Biochem Psychopharmacol Date: 1974

9. Nocturnal elevation of plasma melatonin and urinary 5-hydroxyindoleacetic acid in young men: attempts at modification by brief changes in environmental lighting and sleep and by autonomic drugs.

Authors: G M Vaughan; R W Pelham; S F Pang; L L Loughlin; K M Wilson; K L Sandock; M K Vaughan; S H Koslow; R J Reiter
Journal: J Clin Endocrinol Metab Date: 1976-04 Impact factor: 5.958

10. "Serotonin depression"--a biochemical subgroup within the affective disorders?

Authors: M Asberg; P Thorén; L Träskman; L Bertilsson; V Ringberger
Journal: Science Date: 1976-02-06 Impact factor: 47.728

4 in total

Review 1. Dopamine and depression.

Authors: A S Brown; S Gershon
Journal: J Neural Transm Gen Sect Date: 1993