Literature DB >> 21844315

Wide dissemination of Pseudomonas aeruginosa producing beta-lactamase blaKPC-2 gene in Colombia.

Gaelle Cuzon1, Thierry Naas, Maria-Virginia Villegas, Adriana Correa, John P Quinn, Patrice Nordmann.   

Abstract

Ten bla(KPC-2)-harboring Pseudomonas aeruginosa isolates from hospitals located in five different Colombian cities have been characterized. Isolates were multidrug resistant, belonged to five different pulsotypes, and possessed naturally chromosome-encoded bla(AmpC) and bla(OXA-50) genes and the acquired bla(KPC-2) gene. In most cases, the bla(KPC-2) genes were carried by plasmids of different sizes and were associated with Tn4401b or a new structure containing only part of the Tn4401 sequence. This study revealed that several clones of P. aeruginosa producing bla(KPC-2) are disseminating in Colombia.

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Year:  2011        PMID： 21844315      PMCID： PMC3195029          DOI： 10.1128/AAC.00297-11

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  21 in total

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  25 in total

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Journal:  Antimicrob Agents Chemother       Date:  2012-06-25       Impact factor: 5.191

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3.  Partial excision of blaKPC from Tn4401 in carbapenem-resistant Klebsiella pneumoniae.

Authors:  Liang Chen; Kalyan D Chavda; José R Mediavilla; Michael R Jacobs; Michael H Levi; Robert A Bonomo; Barry N Kreiswirth
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Review 5.  The role of surveillance systems in confronting the global crisis of antibiotic-resistant bacteria.

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6.  Identification and evaluation of twin-arginine translocase inhibitors.

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Review 7.  Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases.

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8.  Similar frequencies of Pseudomonas aeruginosa isolates producing KPC and VIM carbapenemases in diverse genetic clones at tertiary-care hospitals in Medellín, Colombia.

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10.  Complete nucleotide sequences of blaKPC-4- and blaKPC-5-harboring IncN and IncX plasmids from Klebsiella pneumoniae strains isolated in New Jersey.

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Journal:  Antimicrob Agents Chemother       Date:  2012-10-31       Impact factor: 5.191
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