Literature DB >> 2184237

Hydroxyethylamine analogues of the p17/p24 substrate cleavage site are tight-binding inhibitors of HIV protease.

D H Rich1, J Green, M V Toth, G R Marshall, S B Kent.   

Abstract

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 2184237     DOI： 10.1021/jm00167a003

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


× No keyword cloud information.
  13 in total

1.  Thermodynamic linkage between the binding of protons and inhibitors to HIV-1 protease.

Authors:  J Trylska; J Antosiewicz; M Geller; C N Hodge; R M Klabe; M S Head; M K Gilson
Journal:  Protein Sci       Date:  1999-01       Impact factor: 6.725

2.  X-ray crystallographic structure of a complex between a synthetic protease of human immunodeficiency virus 1 and a substrate-based hydroxyethylamine inhibitor.

Authors:  A L Swain; M M Miller; J Green; D H Rich; J Schneider; S B Kent; A Wlodawer
Journal:  Proc Natl Acad Sci U S A       Date:  1990-11       Impact factor: 11.205

3.  Stability and activity of human immunodeficiency virus protease: comparison of the natural dimer with a homologous, single-chain tethered dimer.

Authors:  Y S Cheng; F H Yin; S Foundling; D Blomstrom; C A Kettner
Journal:  Proc Natl Acad Sci U S A       Date:  1990-12       Impact factor: 11.205

Review 4.  Identification of HIV inhibitors guided by free energy perturbation calculations.

Authors:  Orlando Acevedo; Zandrea Ambrose; Patrick T Flaherty; Hadega Aamer; Prashi Jain; Somisetti V Sambasivarao
Journal:  Curr Pharm Des       Date:  2012       Impact factor: 3.116

5.  Insights from atomic-resolution X-ray structures of chemically synthesized HIV-1 protease in complex with inhibitors.

Authors:  Erik C B Johnson; Enrico Malito; Yuequan Shen; Brad Pentelute; Dan Rich; Jan Florián; Wei-Jen Tang; Stephen B H Kent
Journal:  J Mol Biol       Date:  2007-08-02       Impact factor: 5.469

6.  Asymmetric Aldol Route to Hydroxyethylamine Isostere: Stereoselective Synthesis of the Core Unit of Saquinavir.

Authors:  Arun K Ghosh; Khaja Azhar Hussain; Steve Fidanze
Journal:  J Org Chem       Date:  1997-08-22       Impact factor: 4.354

Review 7.  The early years of retroviral protease crystal structures.

Authors:  Maria Miller
Journal:  Biopolymers       Date:  2010       Impact factor: 2.505

8.  In vitro anti-human immunodeficiency virus (HIV) activities of transition state mimetic HIV protease inhibitors containing allophenylnorstatine.

Authors:  S Kageyama; T Mimoto; Y Murakawa; M Nomizu; H Ford; T Shirasaka; S Gulnik; J Erickson; K Takada; H Hayashi
Journal:  Antimicrob Agents Chemother       Date:  1993-04       Impact factor: 5.191

9.  Relative differences in the binding free energies of human immunodeficiency virus 1 protease inhibitors: a thermodynamic cycle-perturbation approach.

Authors:  M R Reddy; V N Viswanadhan; J N Weinstein
Journal:  Proc Natl Acad Sci U S A       Date:  1991-11-15       Impact factor: 11.205

10.  Catalytic contribution of flap-substrate hydrogen bonds in "HIV-1 protease" explored by chemical synthesis.

Authors:  M Baca; S B Kent
Journal:  Proc Natl Acad Sci U S A       Date:  1993-12-15       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.