Literature DB >> 2184127

The relationship between nonsteroidal anti-inflammatory drug use and peptic ulcer disease.

D Y Graham1.   

Abstract

It has become increasingly recognized that nonsteroidal anti-inflammatory drug (NSAID) use is associated with serious gastroduodenal mucosal injury that can eventuate in upper gastrointestinal bleeding or perforation. This article discusses the lack of predictive value of studies administering NSAIDs to normal volunteers. The new data concerning prevention and treatment of chronic NSAID ulcers is also discussed.

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Year:  1990        PMID: 2184127

Source DB:  PubMed          Journal:  Gastroenterol Clin North Am        ISSN: 0889-8553            Impact factor:   3.806


  7 in total

Review 1.  Gastrointestinal complications of nonsteroidal anti-inflammatory drugs.

Authors:  R R Babb
Journal:  West J Med       Date:  1992-10

Review 2.  NSAID-induced gastrointestinal damage. Epidemiology, risk and prevention, with an evaluation of the role of misoprostol. An Asia-Pacific perspective and consensus.

Authors:  G D Champion; P H Feng; T Azuma; D E Caughey; K H Chan; S Kashiwazaki; H C Liu; A R Nasution; M Nobunaga; S Prichanond; T P Torralba; V Udom; D Utis; S R Wang; W S Wong; D J Yang; M C Yoo
Journal:  Drugs       Date:  1997-01       Impact factor: 9.546

Review 3.  We need to integrate new data concerning Helicobacter pylor into experimental ulcer research.

Authors:  D Y Graham
Journal:  Dig Dis Sci       Date:  1995-11       Impact factor: 3.199

4.  Geranylgeranylacetone protects cultured guinea pig gastric mucosal cells from indomethacin.

Authors:  W Tomisato; N Takahashi; C Komoto; K Rokutan; T Tsuchiya; T Mizushima
Journal:  Dig Dis Sci       Date:  2000-08       Impact factor: 3.199

Review 5.  Gastroprotection and nonsteroidal anti-inflammatory drugs (NSAIDS). Rationale and clinical implications.

Authors:  J Hayllar; A Macpherson; I Bjarnason
Journal:  Drug Saf       Date:  1992 Mar-Apr       Impact factor: 5.606

6.  Lack of effects of acemetacin on signalling pathways for leukocyte adherence may explain its gastrointestinal safety.

Authors:  A E Chávez-Piña; L Vong; W McKnight; M Dicay; R C O Zanardo; M I Ortiz; G Castañeda-Hernández; J L Wallace
Journal:  Br J Pharmacol       Date:  2008-08-11       Impact factor: 8.739

7.  Nonsteroidal antiinflammatory drugs could reverse Helicobacter pylori-induced apoptosis and proliferation in gastric epithelial cells.

Authors:  G H Zhu; X L Yang; K C Lai; C K Ching; B C Wong; S T Yuen; J Ho; S K Lam
Journal:  Dig Dis Sci       Date:  1998-09       Impact factor: 3.199

  7 in total

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