| Literature DB >> 9010646 |
G D Champion1, P H Feng, T Azuma, D E Caughey, K H Chan, S Kashiwazaki, H C Liu, A R Nasution, M Nobunaga, S Prichanond, T P Torralba, V Udom, D Utis, S R Wang, W S Wong, D J Yang, M C Yoo.
Abstract
The problem of nonsteroidal anti-inflammatory drug (NSAID)-induced gastrointestinal toxicity was reviewed by members of the Asia Pacific League of Associations for Rheumatology (APLAR) in a consensus conference in September 1992. This paper by the participants presents the consensus conclusions incorporating knowledge from recent publications. There had been a high level of concern that much of the toxicity had resulted from extensive and indiscriminate prescribing of NSAIDs. The implementation of evidence-based guidelines was considered likely to be able to effect a substantial reduction in toxicity without significant loss of overall therapeutic benefit. The evidence from which such guidelines could be developed is critically appraised.Entities:
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Year: 1997 PMID： 9010646 DOI： 10.2165/00003495-199753010-00002
Source DB: PubMed Journal: Drugs ISSN： 0012-6667 Impact factor: 9.546