OBJECTIVE: To examine the associations of sex, body mass index (BMI), and age with knee osteoarthritis (OA) symptomatic severity. DESIGN: A cross-sectional retrospective analysis. SETTING: Patients completed the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire and Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36). Data were acquired from a stored database of a private therapy center. PARTICIPANTS: Patients (N=1487) with symptomatic knee OA were evaluated. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: WOMAC questionnaire and SF-36. RESULTS: BMI correlated significantly with worse knee OA symptoms for all WOMAC and SF-36 subcategories (all P ≤.001). Age correlated significantly with worse symptoms only for WOMAC function and SF-36 physical functioning (P=.001 and P=.009, respectively). A significant difference across BMI quintiles was found for all WOMAC and SF-36 subcategories (all P ≤.01). Women showed worse knee OA symptoms in all WOMAC and SF-36 subcategories (all P ≤.001). There was a significant interaction of sex by BMI in WOMAC pain and WOMAC function (P=.01 and P=.02, respectively). CONCLUSIONS: Based on the results of this analysis, it can be concluded that women and patients with a higher BMI with knee OA are at a greater risk for worse symptoms.
OBJECTIVE: To examine the associations of sex, body mass index (BMI), and age with knee osteoarthritis (OA) symptomatic severity. DESIGN: A cross-sectional retrospective analysis. SETTING:Patients completed the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire and Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36). Data were acquired from a stored database of a private therapy center. PARTICIPANTS: Patients (N=1487) with symptomatic knee OA were evaluated. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: WOMAC questionnaire and SF-36. RESULTS: BMI correlated significantly with worse knee OA symptoms for all WOMAC and SF-36 subcategories (all P ≤.001). Age correlated significantly with worse symptoms only for WOMAC function and SF-36 physical functioning (P=.001 and P=.009, respectively). A significant difference across BMI quintiles was found for all WOMAC and SF-36 subcategories (all P ≤.01). Women showed worse knee OA symptoms in all WOMAC and SF-36 subcategories (all P ≤.001). There was a significant interaction of sex by BMI in WOMAC pain and WOMAC function (P=.01 and P=.02, respectively). CONCLUSIONS: Based on the results of this analysis, it can be concluded that women and patients with a higher BMI with knee OA are at a greater risk for worse symptoms.
Authors: Ron Gilat; Ilan Y Mitchnik; Assaf Moriah; Almog Levi; Ornit Cohen; Dror Lindner; Yiftah Beer; Gabriel Agar Journal: Int Orthop Date: 2022-01-07 Impact factor: 3.075
Authors: N Glass; N A Segal; K A Sluka; J C Torner; M C Nevitt; D T Felson; L A Bradley; T Neogi; C E Lewis; L A Frey-Law Journal: Osteoarthritis Cartilage Date: 2014-07-04 Impact factor: 6.576
Authors: Rachel Jawahar; Shibing Yang; Charles B Eaton; Timothy McAlindon; Kate L Lapane Journal: J Womens Health (Larchmt) Date: 2012-09-04 Impact factor: 2.681