Literature DB >> 21837107

N'-[(E)-2-Meth-oxy-benzyl-idene]pyrazine-2-carbohydrazide.

Marcus V N de Souza, Camilo H da Silva Lima, James L Wardell, Solange M S V Wardell, Edward R T Tiekink.   

Abstract

In the title compound, C(13)H(12)N(4)O(2), all the non-n class="Disease">H atoms lie on a crystallographic mirror plane and an intra-molecular N-H⋯N hydrogen bond generates an S(5) ring; the conformation about the imine bond [1.280 (3) Å] is E. In the crystal, mol-ecules assemble into a two-dimensional array via C-H⋯O(carbon-yl) and C-H⋯N(pyrazine) contacts. Layers stack along the b-axis direction via weak π-π inter-actions between pyrazine rings [ring centroid distance = 3.8028 (8) Å].

Entities:  

Year:  2011        PMID: 21837107      PMCID: PMC3152029          DOI: 10.1107/S1600536811022938

Source DB:  PubMed          Journal:  Acta Crystallogr Sect E Struct Rep Online        ISSN: 1600-5368


  5 in total

1.  Safety and tolerability of intermittent rifampin/pyrazinamide for the treatment of latent tuberculosis infection in prisoners.

Authors:  Richard E Chaisson; Joan Armstrong; John Stafford; Jonathan Golub; Sarah Bur
Journal:  JAMA       Date:  2002-07-10       Impact factor: 56.272

2.  A short history of SHELX.

Authors:  George M Sheldrick
Journal:  Acta Crystallogr A       Date:  2007-12-21       Impact factor: 2.290

3.  Rifampin and pyrazinamide vs isoniazid for prevention of tuberculosis in HIV-infected persons: an international randomized trial. Terry Beirn Community Programs for Clinical Research on AIDS, the Adult AIDS Clinical Trials Group, the Pan American Health Organization, and the Centers for Disease Control and Prevention Study Group.

Authors:  F Gordin; R E Chaisson; J P Matts; C Miller; M de Lourdes Garcia; R Hafner; J L Valdespino; J Coberly; M Schechter; A J Klukowicz; M A Barry; R J O'Brien
Journal:  JAMA       Date:  2000-03-15       Impact factor: 56.272

Review 4.  Promising drugs against tuberculosis.

Authors:  Marcus Vinícius Nora de Souza
Journal:  Recent Pat Antiinfect Drug Discov       Date:  2006-01

5.  Structure validation in chemical crystallography.

Authors:  Anthony L Spek
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2009-01-20
  5 in total

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