Coffee consumption and serum lipids: a randomized, crossover clinical trial.

PURPOSE: The purpose of this study was to determine the effect of consuming three or more cups of filter-brewed coffee per day on levels of serum lipids. SUBJECTS AND METHODS: A prospective, randomized crossover clinical trial was performed. Twenty-one healthy white male subjects completed the trial, and consumed an average of 3.6 cups of coffee a day. Data were evaluated by analysis of variance for repeated measures and t-test for paired means.
RESULTS: No effect of coffee consumption on serum total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, or apolipoprotein B was found. Diet, creamer use, and cigarette use as well as group assignment and time factors were controlled for in the analysis.
CONCLUSION: We found no effect of moderate consumption of filter-brewed coffee on serum levels of atherogenic lipids. This study supports previous work that filtered coffee has no adverse effect on serum lipids. This has far-reaching implications given the widespread use of coffee and the current concern over coronary risk factors.

RCT Entities:   Population Interventions Outcomes