Literature DB >> 21832981

New clinical trials with vitamin D and analogs in renal disease.

Rajiv Kumar.   

Abstract

Two new clinical trials highlight refinements in the use of vitamin D and its analogs in the treatment of secondary hyperparathyroidism in end-stage renal disease (ESRD), and the treatment of proteinuria in diabetics. In patients with ESRD, alfacalcidol is as effective as paricalcitol in suppressing parathyroid hormone; the occurrence of hypercalcemia and hyperphosphatemia is infrequent and similar with the two analogs. Oral cholecalciferol reduces albuminuria and urinary transforming growth factor-β1 in patients with type 2 diabetes mellitus and proteinuria.

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Year:  2011        PMID: 21832981      PMCID: PMC4450646          DOI: 10.1038/ki.2011.260

Source DB:  PubMed          Journal:  Kidney Int        ISSN: 0085-2538            Impact factor:   10.612


  18 in total

Review 1.  Vitamin D metabolism and mechanisms of calcium transport.

Authors:  R Kumar
Journal:  J Am Soc Nephrol       Date:  1990-07       Impact factor: 10.121

2.  Oral cholecalciferol decreases albuminuria and urinary TGF-β1 in patients with type 2 diabetic nephropathy on established renin-angiotensin-aldosterone system inhibition.

Authors:  Min Jeong Kim; Andrew H Frankel; Mandy Donaldson; Sarah J Darch; Charles D Pusey; Peter D Hill; Michael Mayr; Frederick W K Tam
Journal:  Kidney Int       Date:  2011-08-10       Impact factor: 10.612

3.  Selective vitamin D receptor activation with paricalcitol for reduction of albuminuria in patients with type 2 diabetes (VITAL study): a randomised controlled trial.

Authors:  Dick de Zeeuw; Rajiv Agarwal; Michael Amdahl; Paul Audhya; Daniel Coyne; Tushar Garimella; Hans-Henrik Parving; Yili Pritchett; Giuseppe Remuzzi; Eberhard Ritz; Dennis Andress
Journal:  Lancet       Date:  2010-11-06       Impact factor: 79.321

4.  KDOQI US commentary on the 2009 KDIGO Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of CKD-Mineral and Bone Disorder (CKD-MBD).

Authors:  Katrin Uhlig; Jeffrey S Berns; Bryan Kestenbaum; Raj Kumar; Mary B Leonard; Kevin J Martin; Stuart M Sprague; Stanley Goldfarb
Journal:  Am J Kidney Dis       Date:  2010-04-03       Impact factor: 8.860

5.  Short-term effects of vitamin D receptor activation on serum creatinine, creatinine generation, and glomerular filtration.

Authors:  Matthew R Weir
Journal:  Kidney Int       Date:  2011-11       Impact factor: 10.612

Review 6.  The regulation of parathyroid hormone secretion and synthesis.

Authors:  Rajiv Kumar; James R Thompson
Journal:  J Am Soc Nephrol       Date:  2010-12-16       Impact factor: 10.121

7.  1,25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system.

Authors:  Yan Chun Li; Juan Kong; Minjie Wei; Zhou-Feng Chen; Shu Q Liu; Li-Ping Cao
Journal:  J Clin Invest       Date:  2002-07       Impact factor: 14.808

8.  Differential effects of vitamin D receptor activators on vascular calcification in uremic rats.

Authors:  M Mizobuchi; J L Finch; D R Martin; E Slatopolsky
Journal:  Kidney Int       Date:  2007-06-27       Impact factor: 10.612

9.  25-Hydroxyvitamin D levels and albuminuria in the Third National Health and Nutrition Examination Survey (NHANES III).

Authors:  Ian H de Boer; George N Ioannou; Bryan Kestenbaum; John D Brunzell; Noel S Weiss
Journal:  Am J Kidney Dis       Date:  2007-07       Impact factor: 8.860

10.  Oral calcitriol for the treatment of persistent proteinuria in immunoglobulin A nephropathy: an uncontrolled trial.

Authors:  Cheuk-Chun Szeto; Kai-Ming Chow; Bonnie Ching-Ha Kwan; Kwok-Yi Chung; Chi-Bon Leung; Philip Kam-Tao Li
Journal:  Am J Kidney Dis       Date:  2008-04-03       Impact factor: 8.860

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  3 in total

Review 1.  Chronic kidney disease: a new look at pathogenetic mechanisms and treatment options.

Authors:  Damien Noone; Christoph Licht
Journal:  Pediatr Nephrol       Date:  2013-03-08       Impact factor: 3.714

2.  The study of serum vitamin d and insulin resistance in chinese populations with normal glucose tolerance.

Authors:  Lin Ding; Congcong Wang; Heliang Ma; Yuling Tian; Yong Lu; Shuguang Pang
Journal:  Int J Endocrinol       Date:  2014-09-01       Impact factor: 3.257

3.  Comparison of oral and intravenous alfacalcidol in chronic hemodialysis patients.

Authors:  Myriam Lessard; Denis Ouimet; Martine Leblanc; Annie-Claire Nadeau-Fredette; Robert Bell; Jean-Philippe Lafrance; Vincent Pichette; Michel Vallée
Journal:  BMC Nephrol       Date:  2014-02-04       Impact factor: 2.388

  3 in total

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