| Literature DB >> 21832981 |
Abstract
Two new clinical trials highlight refinements in the use of vitamin D and its analogs in the treatment of secondary hyperparathyroidism in end-stage renal disease (ESRD), and the treatment of proteinuria in diabetics. In patients with ESRD, alfacalcidol is as effective as paricalcitol in suppressing parathyroid hormone; the occurrence of hypercalcemia and hyperphosphatemia is infrequent and similar with the two analogs. Oral cholecalciferol reduces albuminuria and urinary transforming growth factor-β1 in patients with type 2 diabetes mellitus and proteinuria.Entities:
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Year: 2011 PMID: 21832981 PMCID: PMC4450646 DOI: 10.1038/ki.2011.260
Source DB: PubMed Journal: Kidney Int ISSN: 0085-2538 Impact factor: 10.612