Literature DB >> 21832945

Intestinal rehabilitation and bowel reconstructive surgery: improved outcomes in children with short bowel syndrome.

Basem A Khalil1, Muhammad E Ba'ath, Anuar Aziz, Lynette Forsythe, Sara Gozzini, Fiona Murphy, Gordon Carlson, Adrian Bianchi, Antonino Morabito.   

Abstract

BACKGROUND AND AIM: Short bowel syndrome poses a great challenge to pediatric teams. Several innovative techniques in the management of total parenteral nutrition (TPN) and bowel reconstructive surgery have improved the outcomes of these children. The authors present their experience during the last decade as a specialist unit using improved techniques and multidisciplinary approaches in the management of this condition.
METHODS: All of the children presenting with short bowel syndrome between 2000 and 2009 were identified. Diagnosis, length of residual gut, age at definitive surgery, length of gut prelengthening, length of gut postlengthening, TPN status, and survival were recorded. Median values were calculated.
RESULTS: Twenty-seven children were identified (14 boys, 13 girls). Overall survival was 92%. Two children died. Nineteen children required bowel lengthening and 8 children had simple bowel reconstruction while on our protocol. Overall median age at definitive surgery was 12 months. Overall median residual gut length for these was 35.5 cm, whereas the median residual gut length for patients undergoing bowel lengthening was 25 cm. Postbowel lengthening, the median gut length was 90 cm. TPN data were unavailable for 2 patients. Overall, excluding the 2 patients who died and the 2 we have no TPN data on, of 23 patients, 21 (91%) are now off TPN.
CONCLUSIONS: Our series shows improved results not only with survival but also in the number of patients that are off TPN. Multidisciplinary approach consisting of both medical and surgical expertise is necessary in the management of these patients. The authors advocate centralisation of short gut services to experienced centers with multidisciplinary expertise.

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Year:  2012        PMID: 21832945     DOI: 10.1097/MPG.0b013e318230c27e

Source DB:  PubMed          Journal:  J Pediatr Gastroenterol Nutr        ISSN: 0277-2116            Impact factor:   2.839


  22 in total

1.  Short bowel syndrome: a practical pathway leading to successful enteral autonomy.

Authors:  M E Ba'ath; S Almond; B King; A Bianchi; B A Khalil; A Morabito
Journal:  World J Surg       Date:  2012-05       Impact factor: 3.352

Review 2.  Autologous intestinal reconstruction surgery as part of comprehensive management of intestinal failure.

Authors:  Mikko P Pakarinen
Journal:  Pediatr Surg Int       Date:  2015-03-29       Impact factor: 1.827

Review 3.  Pediatric short bowel syndrome and subsequent development of inflammatory bowel disease: an illustrative case and literature review.

Authors:  Katherine J Baxter; Jahnavi K Srinivasan; Thomas R Ziegler; Tanvi Dhere; Richard R Ricketts; Megan M Durham
Journal:  Pediatr Surg Int       Date:  2017-04-04       Impact factor: 1.827

Review 4.  Redefining short bowel syndrome in the 21st century.

Authors:  Valeria C Cohran; Joshua D Prozialeck; Conrad R Cole
Journal:  Pediatr Res       Date:  2016-12-20       Impact factor: 3.756

5.  Comparison of polyglycolic acid, polycaprolactone, and collagen as scaffolds for the production of tissue engineered intestine.

Authors:  Yanchun Liu; Tyler Nelson; Jason Chakroff; Barrett Cromeens; Jed Johnson; John Lannutti; Gail E Besner
Journal:  J Biomed Mater Res B Appl Biomater       Date:  2018-09-30       Impact factor: 3.368

6.  Early structured surgical management plan for neonates with short bowel syndrome may improve outcomes.

Authors:  S J Wood; B Khalil; F Fusaro; S E Folaranmi; S A Sparks; A Morabito
Journal:  World J Surg       Date:  2013-07       Impact factor: 3.352

7.  Adaptation: paradigm for the gut and an academic career.

Authors:  Brad W Warner
Journal:  J Pediatr Surg       Date:  2013-01       Impact factor: 2.545

Review 8.  Non-transplant surgery for short bowel syndrome.

Authors:  Alastair J W Millar
Journal:  Pediatr Surg Int       Date:  2013-10       Impact factor: 1.827

9.  Role of Serial Transverse Enteroplasty in the Management of Adult-Type Short Bowel Syndrome: Experience from a Single Tertiary Referral Hospital in Turkey.

Authors:  Muhittin Yaprak; Volkan Doğru; Okan Erdoğan
Journal:  Turk J Gastroenterol       Date:  2021-01       Impact factor: 1.852

10.  Short Bowel Syndrome.

Authors:  Baddr A Shakhsheer; Brad W Warner
Journal:  Curr Treat Options Pediatr       Date:  2019-10-11
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