Literature DB >> 23331788

Adaptation: paradigm for the gut and an academic career.

Brad W Warner1.   

Abstract

Adaptation is an important compensatory response to environmental cues resulting in enhanced survival. In the gut, the abrupt loss of intestinal length is characterized by increased rates of enterocyte proliferation and apoptosis and culminates in adaptive villus and crypt growth. In the development of an academic pediatric surgical career, adaptation is also an important compensatory response to survive the ever changing research, clinical, and economic environment. The ability to adapt in both situations is critical for patients and a legacy of pediatric surgical contributions to advance our knowledge of multiple conditions and diseases.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID: 23331788      PMCID: PMC3552251          DOI: 10.1016/j.jpedsurg.2012.10.014

Source DB:  PubMed          Journal:  J Pediatr Surg        ISSN: 0022-3468            Impact factor:   2.545


  47 in total

Review 1.  Bowel resection induced intestinal adaptation: progress from bench to bedside.

Authors:  S W Longshore; D Wakeman; M McMellen; B W Warner
Journal:  Minerva Pediatr       Date:  2009-06       Impact factor: 1.312

2.  Success in the Pediatric Surgery Match: a survey of the 2010 applicant pool.

Authors:  Alana Beres; Robert Baird; Pramod S Puligandla
Journal:  J Pediatr Surg       Date:  2011-05       Impact factor: 2.545

Review 3.  Intestinal mucosal adaptation.

Authors:  Laurie Drozdowski; Alan B R Thomson
Journal:  World J Gastroenterol       Date:  2006-08-07       Impact factor: 5.742

4.  Body composition and metabolic changes associated with massive intestinal resection in mice.

Authors:  Niramol Tantemsapya; Jareen Meinzner-Derr; Christopher R Erwin; Brad W Warner
Journal:  J Pediatr Surg       Date:  2008-01       Impact factor: 2.545

5.  Retinoblastoma protein (pRb), but not p107 or p130, is required for maintenance of enterocyte quiescence and differentiation in small intestine.

Authors:  Jun Guo; Shannon Longshore; Rajalakshmi Nair; Brad W Warner
Journal:  J Biol Chem       Date:  2008-11-03       Impact factor: 5.157

6.  Long-term nutritional and clinical outcomes after serial transverse enteroplasty at a single institution.

Authors:  Y Avery Ching; Shimae Fitzgibbons; Clarissa Valim; Jing Zhou; Christopher Duggan; Tom Jaksic; Heung Bae Kim
Journal:  J Pediatr Surg       Date:  2009-05       Impact factor: 2.545

7.  Epidermal growth factor receptor signaling modulates apoptosis via p38alpha MAPK-dependent activation of Bax in intestinal epithelial cells.

Authors:  George Sheng; Jun Guo; Brad W Warner
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2007-07-05       Impact factor: 4.052

8.  Resection-induced intestinal adaptation and the role of enteric smooth muscle.

Authors:  Colin A Martin; Kathryn Q Bernabe; Janice A Taylor; Rajalakshmi Nair; Richard J Paul; Jun Guo; Christopher R Erwin; Brad W Warner
Journal:  J Pediatr Surg       Date:  2008-06       Impact factor: 2.545

9.  Intestinal resection induces angiogenesis within adapting intestinal villi.

Authors:  Colin A Martin; Erin E Perrone; Shannon W Longshore; Paul Toste; Kathryn Bitter; Rajalakshmi Nair; Jun Guo; Christopher R Erwin; Brad W Warner
Journal:  J Pediatr Surg       Date:  2009-06       Impact factor: 2.545

10.  p21(waf1/cip1) deficiency does not perturb the intestinal crypt stem cell population after massive small bowel resection.

Authors:  Shannon W Longshore; Rajalakshmi Nair; Erin E Perrone; Christopher R Erwin; Jun Guo; Brad W Warner
Journal:  J Pediatr Surg       Date:  2009-06       Impact factor: 2.545

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