Literature DB >> 21827399

Dietary flavonoids: molecular mechanisms of action as anti- inflammatory agents.

Laura Marzocchella1, Massimo Fantini, Monica Benvenuto, Laura Masuelli, Ilaria Tresoldi, Andrea Modesti, Roberto Bei.   

Abstract

Flavonoids are a large group of polyphenolic compounds, which are ubiquitously expressed in plants. They are grouped according to their chemical structure and function into flavonols, flavones, flavan-3-ols, anthocyanins, flavanones and isoflavones. Many of flavonoids are found in fruits, vegetables and beverages. Flavonoids have been demonstrated to have advantageous effects on human health because their anti-allergic, anti-inflammatory, anti-platelet aggregation, anti-tumor and anti-oxidant behavior. This report reviews the current knowledge on the molecular mechanisms of action of flavonoids as anti-inflammatory agents and also discusses the relevant patents.

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Year:  2011        PMID： 21827399     DOI： 10.2174/187221311797264937

Source DB:  PubMed          Journal:  Recent Pat Inflamm Allergy Drug Discov        ISSN： 1872-213X


  37 in total

1.  Anti-genotoxic ability of α-tocopherol and Anthocyanin to counteract fish DNA damage induced by musk xylene.

Authors:  Lucia Rocco; Filomena Mottola; Marianna Santonastaso; Valentina Saputo; Elena Cusano; Domenico Costagliola; Teresa Suero; Severina Pacifico; Vincenzo Stingo
Journal:  Ecotoxicology       Date:  2015-09-25       Impact factor: 2.823

2.  Evaluation of flavonoid and resveratrol chemical libraries reveals abyssinone II as a promising antibacterial lead.

Authors:  Dianqing Sun; Julian G Hurdle; Robin Lee; Richard Lee; Mark Cushman; John M Pezzuto
Journal:  ChemMedChem       Date:  2012-07-30       Impact factor: 3.466

Review 3.  Polyphenol-Mediated Autophagy in Cancer: Evidence of In Vitro and In Vivo Studies.

Authors:  Monica Benvenuto; Loredana Albonici; Chiara Focaccetti; Sara Ciuffa; Sara Fazi; Loredana Cifaldi; Martino Tony Miele; Fernando De Maio; Ilaria Tresoldi; Vittorio Manzari; Andrea Modesti; Laura Masuelli; Roberto Bei
Journal:  Int J Mol Sci       Date:  2020-09-10       Impact factor: 5.923

4.  Ellagic acid promotes A549 cell apoptosis via regulating the phosphoinositide 3-kinase/protein kinase B pathway.

Authors:  Qiong Liu; Xiaobing Liang; Chengwei Niu; Xuelan Wang
Journal:  Exp Ther Med       Date:  2018-05-18       Impact factor: 2.447

Review 5.  Polyphenols, inflammation, and cardiovascular disease.

Authors:  Christy C Tangney; Heather E Rasmussen
Journal:  Curr Atheroscler Rep       Date:  2013-05       Impact factor: 5.113

6.  Resveratrol potentiates the in vitro and in vivo anti-tumoral effects of curcumin in head and neck carcinomas.

Authors:  Laura Masuelli; Enrica Di Stefano; Massimo Fantini; Rosanna Mattera; Monica Benvenuto; Laura Marzocchella; Pamela Sacchetti; Chiara Focaccetti; Roberta Bernardini; Ilaria Tresoldi; Valerio Izzi; Maurizio Mattei; Giovanni Vanni Frajese; Florigio Lista; Andrea Modesti; Roberto Bei
Journal:  Oncotarget       Date:  2014-11-15

Review 7.  Polyphenols Modulating Effects of PD-L1/PD-1 Checkpoint and EMT-Mediated PD-L1 Overexpression in Breast Cancer.

Authors:  Samia S Messeha; Najla O Zarmouh; Karam F A Soliman
Journal:  Nutrients       Date:  2021-05-19       Impact factor: 5.717

8.  Protective role of malvidin-3-glucoside on peroxynitrite-induced damage in endothelial cells by counteracting reactive species formation and apoptotic mitochondrial pathway.

Authors:  Joana Paixão; Teresa C P Dinis; Leonor M Almeida
Journal:  Oxid Med Cell Longev       Date:  2012-06-20       Impact factor: 6.543

Review 9.  In vitro and in vivo antitumoral effects of combinations of polyphenols, or polyphenols and anticancer drugs: perspectives on cancer treatment.

Authors:  Massimo Fantini; Monica Benvenuto; Laura Masuelli; Giovanni Vanni Frajese; Ilaria Tresoldi; Andrea Modesti; Roberto Bei
Journal:  Int J Mol Sci       Date:  2015-04-24       Impact factor: 5.923

10.  Modified Glasgow Prognostic Score is Associated With Risk of Recurrence in Bladder Cancer Patients After Radical Cystectomy: A Multicenter Experience.

Authors:  Matteo Ferro; Ottavio De Cobelli; Carlo Buonerba; Giuseppe Di Lorenzo; Marco Capece; Dario Bruzzese; Riccardo Autorino; Danilo Bottero; Antonio Cioffi; Deliu Victor Matei; Michele Caraglia; Marco Borghesi; Ettore De Berardinis; Gian Maria Busetto; Riccardo Giovannone; Giuseppe Lucarelli; Pasquale Ditonno; Sisto Perdonà; Pierluigi Bove; Luigi Castaldo; Rodolfo Hurle; Gennaro Musi; Antonio Brescia; Michele Olivieri; Amelia Cimmino; Vincenzo Altieri; Rocco Damiano; Francesco Cantiello; Vincenzo Serretta; Sabino De Placido; Vincenzo Mirone; Guru Sonpavde; Daniela Terracciano
Journal:  Medicine (Baltimore)       Date:  2015-10       Impact factor: 1.817
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