Literature DB >> 21826600

Delaying vascular aging with Chinese medicine: implications from an overview of the p53 and miR-34s family.

Ming Wang1, Yan Lei.   

Abstract

p53 is an important target for studying vascular aging. However, as people gradually learned more about the miR-34s and the relationship between miR-34s and p53, new research idea emerged. This paper tries to elaborate the feature of p53, microRNA and miR-34s in-depth, analyze the regulatory action of miR-34s on p53, and offer some new prevention and treatment prospects about vascular aging in Chinese medicine.

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Year:  2011        PMID： 21826600     DOI： 10.1007/s11655-011-0823-y

Source DB:  PubMed          Journal:  Chin J Integr Med        ISSN： 1672-0415            Impact factor:   1.978


  34 in total

1.  PML regulates p53 acetylation and premature senescence induced by oncogenic Ras.

Authors:  M Pearson; R Carbone; C Sebastiani; M Cioce; M Fagioli; S Saito; Y Higashimoto; E Appella; S Minucci; P P Pandolfi; P G Pelicci
Journal:  Nature       Date:  2000-07-13       Impact factor: 49.962

Review 2.  The evolution of diverse biological responses to DNA damage: insights from yeast and p53.

Authors:  G M Wahl; A M Carr
Journal:  Nat Cell Biol       Date:  2001-12       Impact factor: 28.824

Review 3.  microRNAs join the p53 network--another piece in the tumour-suppression puzzle.

Authors:  Lin He; Xingyue He; Scott W Lowe; Gregory J Hannon
Journal:  Nat Rev Cancer       Date:  2007-11       Impact factor: 60.716

4.  Multiple p53-independent gene silencing mechanisms define the cellular response to p53 activation.

Authors:  Ramiro París; Ryan E Henry; Sarah J Stephens; Meagan McBryde; Joaquín M Espinosa
Journal:  Cell Cycle       Date:  2008-06-09       Impact factor: 4.534

Review 5.  Cellular senescence as a tumor-suppressor mechanism.

Authors:  J Campisi
Journal:  Trends Cell Biol       Date:  2001-11       Impact factor: 20.808

6.  Angiotensin II induces premature senescence of vascular smooth muscle cells and accelerates the development of atherosclerosis via a p21-dependent pathway.

Authors:  Takeshige Kunieda; Tohru Minamino; Jun-Ichiro Nishi; Kaoru Tateno; Tomomi Oyama; Taro Katsuno; Hideyuki Miyauchi; Masayuki Orimo; Sho Okada; Masayuki Takamura; Toshio Nagai; Shuichi Kaneko; Issei Komuro
Journal:  Circulation       Date:  2006-08-14       Impact factor: 29.690

7.  MiR-34, SIRT1 and p53: the feedback loop.

Authors:  Munekazu Yamakuchi; Charles J Lowenstein
Journal:  Cell Cycle       Date:  2009-03-02       Impact factor: 4.534

8.  p53-mediated activation of miRNA34 candidate tumor-suppressor genes.

Authors:  Guido T Bommer; Isabelle Gerin; Ying Feng; Andrew J Kaczorowski; Rork Kuick; Robert E Love; Yali Zhai; Thomas J Giordano; Zhaohui S Qin; Bethany B Moore; Ormond A MacDougald; Kathleen R Cho; Eric R Fearon
Journal:  Curr Biol       Date:  2007-07-26       Impact factor: 10.834

9.  Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest.

Authors:  Valery Tarasov; Peter Jung; Berlinda Verdoodt; Dmitri Lodygin; Alexey Epanchintsev; Antje Menssen; Gunter Meister; Heiko Hermeking
Journal:  Cell Cycle       Date:  2007-05-11       Impact factor: 4.534

10.  Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis.

Authors:  Tsung-Cheng Chang; Erik A Wentzel; Oliver A Kent; Kalyani Ramachandran; Michael Mullendore; Kwang Hyuck Lee; Georg Feldmann; Munekazu Yamakuchi; Marcella Ferlito; Charles J Lowenstein; Dan E Arking; Michael A Beer; Anirban Maitra; Joshua T Mendell
Journal:  Mol Cell       Date:  2007-05-31       Impact factor: 17.970
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  3 in total

1.  Time-effect relationship of extracts from ginseng, notoginseng and chuanxiong on vascular endothelial cells senescence.

Authors:  Ming Wang; Yan Lei
Journal:  Chin J Integr Med       Date:  2014-07-30       Impact factor: 1.978

2.  Effects of rhein lysinate on D-galactose-induced aging mice.

Authors:  Yong-Zhan Zhen; Ya-Jun Lin; Kai-Ji Li; Guang-Ling Zhang; Yu-Fang Zhao; Mei-Mei Wang; Jing-Bo Wei; Jie Wei; Gang Hu
Journal:  Exp Ther Med       Date:  2015-11-12       Impact factor: 2.447

Review 3.  Molecular dynamic simulation insights into the normal state and restoration of p53 function.

Authors:  Ting Fu; Hanyi Min; Yong Xu; Jianzhong Chen; Guohui Li
Journal:  Int J Mol Sci       Date:  2012-08-03       Impact factor: 6.208
  3 in total

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