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Literature DB >> 21826282

Transcription of ncDNA: Many roads lead to local gene regulation.

Abstract

Transcription of ncDNA occurs throughout eukaryotic genomes, generating a wide array of ncRNAs. One large class of ncRNAs includes those transcribed over the promoter regions of nearby protein coding genes. Recent studies, primarily focusing on individual genes have uncovered multiple mechanisms by which promoter-associated transcriptional activity locally alters gene expression.

Year: 2011 PMID： 21826282 PMCID： PMC3149688 DOI： 10.4161/trns.2.3.15684

Source DB: PubMed Journal: Transcription ISSN： 2154-1272

34 in total

1. The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription.

Authors: Yonggang Zhou; Raffaella Santoro; Ingrid Grummt
Journal: EMBO J Date: 2002-09-02 Impact factor: 11.598

2. Interaction of noncoding RNA with the rDNA promoter mediates recruitment of DNMT3b and silencing of rRNA genes.

Authors: Kerstin-Maike Schmitz; Christine Mayer; Anna Postepska; Ingrid Grummt
Journal: Genes Dev Date: 2010-10-15 Impact factor: 11.361

Review 3. A site to remember: H3K36 methylation a mark for histone deacetylation.

Authors: Jung-Shin Lee; Ali Shilatifard
Journal: Mutat Res Date: 2007-01-21 Impact factor: 2.433

Review 4. The complex eukaryotic transcriptome: unexpected pervasive transcription and novel small RNAs.

Authors: Alain Jacquier
Journal: Nat Rev Genet Date: 2009-12 Impact factor: 53.242

5. Intergenic transcription causes repression by directing nucleosome assembly.

Authors: Sarah J Hainer; Justin A Pruneski; Rachel D Mitchell; Robin M Monteverde; Joseph A Martens
Journal: Genes Dev Date: 2010-12-14 Impact factor: 11.361

6. Properties of an intergenic terminator and start site switch that regulate IMD2 transcription in yeast.

Authors: M Harley Jenks; Thomas W O'Rourke; Daniel Reines
Journal: Mol Cell Biol Date: 2008-04-21 Impact factor: 4.272

7. Discrete human dihydrofolate reductase gene transcripts present in polysomal RNA map with their 5' ends several hundred nucleotides upstream of the main mRNA start site.

Authors: J N Masters; G Attardi
Journal: Mol Cell Biol Date: 1985-03 Impact factor: 4.272

Transcription of ncDNA: Many roads lead to local gene regulation.

1. The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription.

2. Interaction of noncoding RNA with the rDNA promoter mediates recruitment of DNMT3b and silencing of rRNA genes.

Review 3. A site to remember: H3K36 methylation a mark for histone deacetylation.

Review 4. The complex eukaryotic transcriptome: unexpected pervasive transcription and novel small RNAs.

5. Intergenic transcription causes repression by directing nucleosome assembly.

6. Properties of an intergenic terminator and start site switch that regulate IMD2 transcription in yeast.

7. Discrete human dihydrofolate reductase gene transcripts present in polysomal RNA map with their 5' ends several hundred nucleotides upstream of the main mRNA start site.

8. Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA.

9. Bidirectional promoters generate pervasive transcription in yeast.

Review 10. The Polycomb complex PRC2 and its mark in life.

1. Alternative transcription start site selection leads to large differences in translation activity in yeast.

Review 2. Long Non-coding RNAs in Tuberculosis: From Immunity to Biomarkers.

Review 3. A Mechanistic Theory of Development-Aging Continuity in Humans and Other Mammals.