Literature DB >> 21826281

Phosphorylation of RNAPII: To P-TEFb or not to P-TEFb?

Bartlomiej Bartkowiak1, Arno L Greenleaf.   

Abstract

The C-terminal domain of RNA polymerase II undergoes a cycle of phosphorylation which allows it to temporally couple transcription with transcription-associated processes. The characterization of hitherto unrecognized metazoan elongation phase CTD kinase activities expands our understanding of this coupling. We discuss the circumstances that delayed the recognition of these kinase activities.

Entities:  

Year:  2011        PMID： 21826281      PMCID： PMC3149687          DOI： 10.4161/trns.2.3.15004

Source DB:  PubMed          Journal:  Transcription        ISSN： 2154-1272


  31 in total

1.  Evolution of cyclin-dependent kinases (CDKs) and CDK-activating kinases (CAKs): differential conservation of CAKs in yeast and metazoa.

Authors:  J Liu; E T Kipreos
Journal:  Mol Biol Evol       Date:  2000-07       Impact factor: 16.240

Review 2.  Progression through the RNA polymerase II CTD cycle.

Authors:  Stephen Buratowski
Journal:  Mol Cell       Date:  2009-11-25       Impact factor: 17.970

3.  Phosphorylation of the Pol II CTD by KIN28 enhances BUR1/BUR2 recruitment and Ser2 CTD phosphorylation near promoters.

Authors:  Hongfang Qiu; Cuihua Hu; Alan G Hinnebusch
Journal:  Mol Cell       Date:  2009-03-27       Impact factor: 17.970

4.  C-terminal repeat domain kinase I phosphorylates Ser2 and Ser5 of RNA polymerase II C-terminal domain repeats.

Authors:  Janice C Jones; Hemali P Phatnani; Timothy A Haystead; Justin A MacDonald; S Munir Alam; Arno L Greenleaf
Journal:  J Biol Chem       Date:  2004-03-26       Impact factor: 5.157

5.  Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK.

Authors:  W J Feaver; J Q Svejstrup; N L Henry; R D Kornberg
Journal:  Cell       Date:  1994-12-16       Impact factor: 41.582

6.  Characterization of the Schizosaccharomyces pombe Cdk9/Pch1 protein kinase: Spt5 phosphorylation, autophosphorylation, and mutational analysis.

Authors:  Yi Pei; Stewart Shuman
Journal:  J Biol Chem       Date:  2003-08-05       Impact factor: 5.157

7.  A protein kinase that phosphorylates the C-terminal repeat domain of the largest subunit of RNA polymerase II.

Authors:  J M Lee; A L Greenleaf
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

8.  CrkRS: a novel conserved Cdc2-related protein kinase that colocalises with SC35 speckles.

Authors:  T K Ko; E Kelly; J Pines
Journal:  J Cell Sci       Date:  2001-07       Impact factor: 5.285

9.  Comparative genomics of cyclin-dependent kinases suggest co-evolution of the RNAP II C-terminal domain and CTD-directed CDKs.

Authors:  Zhenhua Guo; John W Stiller
Journal:  BMC Genomics       Date:  2004-09-20       Impact factor: 3.969

10.  A cyclin-dependent kinase that promotes cytokinesis through modulating phosphorylation of the carboxy terminal domain of the RNA Pol II Rpb1p sub-unit.

Authors:  Jim Karagiannis; Mohan K Balasubramanian
Journal:  PLoS One       Date:  2007-05-09       Impact factor: 3.240
View more
  25 in total

Review 1.  RNA polymerase II elongation control.

Authors:  Qiang Zhou; Tiandao Li; David H Price
Journal:  Annu Rev Biochem       Date:  2012-03-09       Impact factor: 23.643

2.  Phosphorylation of RNA polymerase II is independent of P-TEFb in the C. elegans germline.

Authors:  Elizabeth Anne Bowman; Christopher Ray Bowman; Jeong H Ahn; William G Kelly
Journal:  Development       Date:  2013-07-31       Impact factor: 6.868

Review 3.  RNA polymerase II C-terminal domain: Tethering transcription to transcript and template.

Authors:  Jeffry L Corden
Journal:  Chem Rev       Date:  2013-09-16       Impact factor: 60.622

4.  Phosphorylation of HEXIM1 at Tyr271 and Tyr274 Promotes Release of P-TEFb from the 7SK snRNP Complex and Enhances Proviral HIV Gene Expression.

Authors:  Uri R Mbonye; Benlian Wang; Giridharan Gokulrangan; Mark R Chance; Jonathan Karn
Journal:  Proteomics       Date:  2015-05-15       Impact factor: 3.984

Review 5.  Repression of somatic cell fate in the germline.

Authors:  Valérie J Robert; Steve Garvis; Francesca Palladino
Journal:  Cell Mol Life Sci       Date:  2015-06-05       Impact factor: 9.261

6.  Evolutionary diversity and taxon-specific modifications of the RNA polymerase II C-terminal domain.

Authors:  Chunlin Yang; John W Stiller
Journal:  Proc Natl Acad Sci U S A       Date:  2014-04-07       Impact factor: 11.205

7.  Function and control of RNA polymerase II C-terminal domain phosphorylation in vertebrate transcription and RNA processing.

Authors:  Jing-Ping Hsin; Kehui Xiang; James L Manley
Journal:  Mol Cell Biol       Date:  2014-04-21       Impact factor: 4.272

8.  Structural determinants for accurate dephosphorylation of RNA polymerase II by its cognate C-terminal domain (CTD) phosphatase during eukaryotic transcription.

Authors:  Seema Irani; Sarah N Sipe; Wanjie Yang; Nathaniel T Burkholder; Brian Lin; Kelly Sim; Wendy L Matthews; Jennifer S Brodbelt; Yan Zhang
Journal:  J Biol Chem       Date:  2019-04-10       Impact factor: 5.157

Review 9.  O-GlcNAc and the epigenetic regulation of gene expression.

Authors:  Brian A Lewis; John A Hanover
Journal:  J Biol Chem       Date:  2014-10-21       Impact factor: 5.157

10.  The identification of putative RNA polymerase II C-terminal domain associated proteins in red and green algae.

Authors:  Chunlin Yang; Paul W Hager; John W Stiller
Journal:  Transcription       Date:  2014-12-10
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.