Literature DB >> 21824556

Current and future pharmacologic treatment of sarcopenia.

Yves Rolland1, Graziano Onder, John E Morley, Sophie Gillette-Guyonet, Gabor Abellan van Kan, Bruno Vellas.   

Abstract

Sarcopenia is a complex multifactorial condition that can by treated with multimodal approaches. No pharmacologic agent to prevent or treat sarcopenia has been as efficacious as exercise (mainly resistance training) in combination with nutritional intervention (adequate protein and energy intake). However, performing resistance training sessions and following nutritional advice can be challenging, especially for frail, sarcopenic, elderly patients, and results remain only partial. Therefore, new pharmacologic agents may substantially reduce the functional decline in older people. This article reviews the new pharmacologic agents currently being assessed for treating sarcopenia.
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID： 21824556     DOI： 10.1016/j.cger.2011.03.008

Source DB:  PubMed          Journal:  Clin Geriatr Med        ISSN： 0749-0690            Impact factor:   3.076


  25 in total

Review 1.  Muscle atrophy in aging and chronic diseases: is it sarcopenia or cachexia?

Authors:  Maurizio Muscaritoli; Simone Lucia; Alessio Molfino; Tommy Cederholm; Filippo Rossi Fanelli
Journal:  Intern Emerg Med       Date:  2012-07-08       Impact factor: 3.397

Review 2.  A four-season molecule: osteocalcin. Updates in its physiological roles.

Authors:  Giovanni Lombardi; Silvia Perego; Livio Luzi; Giuseppe Banfi
Journal:  Endocrine       Date:  2014-08-27       Impact factor: 3.633

Review 3.  Quality of life in sarcopenia and frailty.

Authors:  René Rizzoli; Jean-Yves Reginster; Jean-François Arnal; Ivan Bautmans; Charlotte Beaudart; Heike Bischoff-Ferrari; Emmanuel Biver; Steven Boonen; Maria-Luisa Brandi; Arkadi Chines; Cyrus Cooper; Sol Epstein; Roger A Fielding; Bret Goodpaster; John A Kanis; Jean-Marc Kaufman; Andrea Laslop; Vincenzo Malafarina; Leocadio Rodriguez Mañas; Bruce H Mitlak; Richard O Oreffo; Jean Petermans; Kieran Reid; Yves Rolland; Avan Aihie Sayer; Yannis Tsouderos; Marjolein Visser; Olivier Bruyère
Journal:  Calcif Tissue Int       Date:  2013-07-05       Impact factor: 4.333

4.  The Importance of Geriatric Syndromes.

Authors:  John E Morley
Journal:  Mo Med       Date:  2017 Mar-Apr

5.  Nutritional status and COVID-19: an opportunity for lasting change?

Authors:  Shameer Mehta
Journal:  Clin Med (Lond)       Date:  2020-04-27       Impact factor: 2.659

6.  Effect of Antihypertensive and Statin Medication Use on Muscle Performance in Community-Dwelling Older Adults Performing Strength Training.

Authors:  Mohammad Alturki; Keliane Liberman; Andreas Delaere; Liza De Dobbeleer; Veerle Knoop; Tony Mets; Siddhartha Lieten; Bert Bravenboer; Ingo Beyer; Ivan Bautmans
Journal:  Drugs Aging       Date:  2021-02-05       Impact factor: 3.923

7.  Angiotensin-Converting Enzyme Inhibitors and Parameters of Sarcopenia: Relation to Muscle Mass, Strength and Function: Data from the Berlin Aging Study-II (BASE-II).

Authors:  Dominik Spira; Jeremy Walston; Nikolaus Buchmann; Jivko Nikolov; Ilja Demuth; Elisabeth Steinhagen-Thiessen; Rahel Eckardt; Kristina Norman
Journal:  Drugs Aging       Date:  2016-11       Impact factor: 3.923

8.  Reproducibility of jumping mechanography and traditional measures of physical and muscle function in older adults.

Authors:  B Buehring; D Krueger; E Fidler; R Gangnon; B Heiderscheit; N Binkley
Journal:  Osteoporos Int       Date:  2014-12-09       Impact factor: 4.507

9.  Sarcopenia and osteoporosis in Portuguese centenarians.

Authors:  A P da Silva; A Matos; R Ribeiro; Â Gil; A Valente; M Bicho; J Gorjão-Clara
Journal:  Eur J Clin Nutr       Date:  2016-09-21       Impact factor: 4.016

10.  Frailty consensus: a call to action.

Authors:  John E Morley; Bruno Vellas; G Abellan van Kan; Stefan D Anker; Juergen M Bauer; Roberto Bernabei; Matteo Cesari; W C Chumlea; Wolfram Doehner; Jonathan Evans; Linda P Fried; Jack M Guralnik; Paul R Katz; Theodore K Malmstrom; Roger J McCarter; Luis M Gutierrez Robledo; Ken Rockwood; Stephan von Haehling; Maurits F Vandewoude; Jeremy Walston
Journal:  J Am Med Dir Assoc       Date:  2013-06       Impact factor: 4.669
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