| Literature DB >> 21822055 |
Betty P K Poon1, Karim Mekhail.
Abstract
Interactions between genetic regions located across the genome maintain its three-dimensional organization and function. Recent studies point to key roles for a set of coiled-coil domain-containing complexes (cohibin, cohesin, condensin and monopolin) and related factors in the regulation of DNA-DNA connections across the genome. These connections are critical to replication, recombination, gene expression as well as chromosome segregation.Mesh:
Substances:
Year: 2011 PMID: 21822055 PMCID: PMC3219537 DOI: 10.4161/cc.10.16.17113
Source DB: PubMed Journal: Cell Cycle ISSN: 1551-4005 Impact factor: 4.534