| Literature DB >> 21818123 |
Michael Gleeson1, Nicolette C Bishop, David J Stensel, Martin R Lindley, Sarabjit S Mastana, Myra A Nimmo.
Abstract
Regular exercise reduces the risk of chronic metabolic and cardiorespiratory diseases, in part because exercise exerts anti-inflammatory effects. However, these effects are also likely to be responsible for the suppressed immunity that makes elite athletes more susceptible to infections. The anti-inflammatory effects of regular exercise may be mediated via both a reduction in visceral fat mass (with a subsequent decreased release of adipokines) and the induction of an anti-inflammatory environment with each bout of exercise. In this Review, we focus on the known mechanisms by which exercise - both acute and chronic - exerts its anti-inflammatory effects, and we discuss the implications of these effects for the prevention and treatment of disease.Entities:
Mesh：
Substances：
Year: 2011 PMID： 21818123 DOI： 10.1038/nri3041
Source DB: PubMed Journal: Nat Rev Immunol ISSN： 1474-1733 Impact factor: 53.106