| Literature DB >> 21802004 |
James J Cronican1, Kevin T Beier, Tina N Davis, Jen-Chieh Tseng, Weida Li, David B Thompson, Allen F Shih, Erin M May, Constance L Cepko, Andrew L Kung, Qiao Zhou, David R Liu.
Abstract
We discovered a class of naturally occurring human proteins with unusually high net positive charge that can potently deliver proteins in functional form into mammalian cells both in vitro and also in murine retina, pancreas, and white adipose tissues in vivo. These findings represent diverse macromolecule delivery agents for in vivo applications, and also raise the possibility that some of these human proteins may penetrate cells as part of their native biological functions.Entities:
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Year: 2011 PMID： 21802004 PMCID： PMC3154086 DOI： 10.1016/j.chembiol.2011.07.003
Source DB: PubMed Journal: Chem Biol ISSN： 1074-5521