Literature DB >> 21800532

[Multidrug resistance-associated proteins and their roles in multidrug resistance].

Hui Zhang1, Li-wu Fu.   

Abstract

Multidrug resistance (MDR) is a major impediment to the success of cancer chemotherapy. Multidrug resistance-associated proteins (MRPs) play an important role in the process of MDR. As an ATP-binding cassette (ABC) transporter superfamily, MRPs are selective and specific drug efflux pumps. In this paper, physiological characteristics, structural characteristics and resistance profile of MRPs and the associated reversal studies are reviewed.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21800532

Source DB:  PubMed          Journal:  Yao Xue Xue Bao        ISSN： 0513-4870


  4 in total

1.  Overexpression of ABCC3 promotes cell proliferation, drug resistance, and aerobic glycolysis and is associated with poor prognosis in urinary bladder cancer patients.

Authors:  Xuejun Liu; Dongwei Yao; Cheng Liu; Yunjian Cao; Qiurong Yang; Zhichao Sun; Duo Liu
Journal:  Tumour Biol       Date:  2016-01-05

2.  Berberine Reverses Breast Cancer Multidrug Resistance Based on Fluorescence Pharmacokinetics In Vitro and In Vivo.

Authors:  Ke Qian; Chao-Yuan Tang; Li-Ying Chen; Shuang Zheng; Yue Zhao; Li-Sha Ma; Li Xu; Lu-Hui Fan; Jian-Dong Yu; Hong-Sheng Tan; Ya-Lan Sun; Li-Li Shen; Yang Lu; Qi Liu; Yun Liu; Yang Xiong
Journal:  ACS Omega       Date:  2021-04-13

Review 3.  Drug resistance: from bacteria to cancer.

Authors:  Harsh Patel; Zhuo-Xun Wu; Yanglu Chen; Letao Bo; Zhe-Sheng Chen
Journal:  Mol Biomed       Date:  2021-09-10

4.  Case Report: Three novel pathogenic ABCC2 mutations identified in two patients with Dubin-Johnson syndrome.

Authors:  Chenyu Zhao; Xiaoliu Shi; Yonghong Zhang; Hui Huang
Journal:  Front Genet       Date:  2022-08-25       Impact factor: 4.772
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.