Literature DB >> 21796634

A million africans a year dying from cancer by 2030: what can cancer research and control offer to the continent?

Bakary S Sylla1, Christopher P Wild.   

Abstract

In Africa, there were an estimated 681,000 new cancer cases and 512,000 deaths in 2008. Projections to 2030 show a startling rise, with corresponding figures of 1.27 million cases and 0.97 million deaths resulting from population growth and aging alone. The figures make no assumptions about incidence rates which may increase due to the further introduction of tobacco and a more westernized lifestyle. The current situation in many parts of Africa with respect to health care systems suggests that improved cancer treatment would be an insufficient response to this increasing burden. Much could be achieved through cancer prevention by applying current knowledge about major risk factors and the natural history of the disease. For example, vaccination against hepatitis B virus and human papilloma viruses would prevent the occurrence of two of the most common cancers in Africa, liver and cervix, respectively, in the long-term. Strong measures to prevent the widespread introduction of tobacco must be a priority. Early detection and treatment of cervical and breast cancers using approaches applicable now in Africa would provide immediate value, as would the management of human immunodeficiency virus (HIV) infection in respect to HIV-associated malignancies. In parallel, further research is needed into the causes of cancer and the barriers to implementation of promising prevention strategies. Underpinning all is the need for African governments to look forward and prioritize cancer through national cancer control plans, to invest in public health infrastructure and to ensure the adequate training and support for people in cancer prevention and control. Given this core commitment from within Africa, international partners can provide complementary support in a cooperation that permits action now to mitigate the impending tragedy of cancer in the continent of Africa.
Copyright © 2011 UICC.

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Year:  2011        PMID: 21796634      PMCID: PMC3244688          DOI: 10.1002/ijc.26333

Source DB:  PubMed          Journal:  Int J Cancer        ISSN: 0020-7136            Impact factor:   7.396


  22 in total

1.  A review of human carcinogens--Part B: biological agents.

Authors:  Véronique Bouvard; Robert Baan; Kurt Straif; Yann Grosse; Béatrice Secretan; Fatiha El Ghissassi; Lamia Benbrahim-Tallaa; Neela Guha; Crystal Freeman; Laurent Galichet; Vincent Cogliano
Journal:  Lancet Oncol       Date:  2009-04       Impact factor: 41.316

Review 2.  Part I: Cancer in Indigenous Africans--burden, distribution, and trends.

Authors:  D Max Parkin; Freddy Sitas; Mike Chirenje; Lara Stein; Raymond Abratt; Henry Wabinga
Journal:  Lancet Oncol       Date:  2008-07       Impact factor: 41.316

3.  Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008.

Authors:  Jacques Ferlay; Hai-Rim Shin; Freddie Bray; David Forman; Colin Mathers; Donald Maxwell Parkin
Journal:  Int J Cancer       Date:  2010-12-15       Impact factor: 7.396

4.  Fumonisin B1 as a urinary biomarker of exposure in a maize intervention study among South African subsistence farmers.

Authors:  Liana van der Westhuizen; Gordon S Shephard; Hester M Burger; John P Rheeder; Wentzel C A Gelderblom; Christopher P Wild; Yun Yun Gong
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2011-01-25       Impact factor: 4.254

5.  Mycotoxins and human disease: a largely ignored global health issue.

Authors:  Christopher P Wild; Yun Yun Gong
Journal:  Carcinogenesis       Date:  2009-10-29       Impact factor: 4.944

6.  Decreased incidence of hepatocellular carcinoma in hepatitis B vaccinees: a 20-year follow-up study.

Authors:  Mei-Hwei Chang; San-Lin You; Chien-Jen Chen; Chun-Jen Liu; Chuan-Mo Lee; Shi-Ming Lin; Heng-Cheng Chu; Tzee-Chung Wu; Sheng-Shun Yang; Hsu-Sung Kuo; Ding-Shinn Chen
Journal:  J Natl Cancer Inst       Date:  2009-09-16       Impact factor: 13.506

7.  Changing cancer incidence in Kampala, Uganda, 1991-2006.

Authors:  Donald Maxwell Parkin; Sarah Nambooze; Fred Wabwire-Mangen; Henry R Wabinga
Journal:  Int J Cancer       Date:  2010-03-01       Impact factor: 7.396

8.  HPV screening for cervical cancer in rural India.

Authors:  Rengaswamy Sankaranarayanan; Bhagwan M Nene; Surendra S Shastri; Kasturi Jayant; Richard Muwonge; Atul M Budukh; Sanjay Hingmire; Sylla G Malvi; Ranjit Thorat; Ashok Kothari; Roshan Chinoy; Rohini Kelkar; Shubhada Kane; Sangeetha Desai; Vijay R Keskar; Raghevendra Rajeshwarkar; Nandkumar Panse; Ketayun A Dinshaw
Journal:  N Engl J Med       Date:  2009-04-02       Impact factor: 91.245

9.  Overweight and obesity in urban Africa: A problem of the rich or the poor?

Authors:  Abdhalah K Ziraba; Jean C Fotso; Rhoune Ochako
Journal:  BMC Public Health       Date:  2009-12-15       Impact factor: 3.295

10.  20 years into the Gambia Hepatitis Intervention Study: assessment of initial hypotheses and prospects for evaluation of protective effectiveness against liver cancer.

Authors:  Simonetta Viviani; Patrizia Carrieri; Ebrima Bah; Andrew J Hall; Gregory D Kirk; Maimuna Mendy; Ruggero Montesano; Amelie Plymoth; Omar Sam; Marianne Van der Sande; Hilton Whittle; Pierre Hainaut
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2008-11       Impact factor: 4.254

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  67 in total

1.  Cancer incidence in Nigeria: a report from population-based cancer registries.

Authors:  Elima Jedy-Agba; Maria Paula Curado; Olufemi Ogunbiyi; Emmanuel Oga; Toyin Fabowale; Festus Igbinoba; Gloria Osubor; Theresa Otu; Henry Kumai; Alice Koechlin; Patience Osinubi; Patrick Dakum; William Blattner; Clement A Adebamowo
Journal:  Cancer Epidemiol       Date:  2012-05-22       Impact factor: 2.984

2.  HIV and cancer in Africa: mutual collaboration between HIV and cancer programs may provide timely research and public health data.

Authors:  Sam M Mbulaiteye; Kishor Bhatia; Clement Adebamowo; Annie J Sasco
Journal:  Infect Agent Cancer       Date:  2011-10-17       Impact factor: 2.965

3.  Integrating genetic and genomic information into effective cancer care in diverse populations.

Authors:  L Fashoyin-Aje; K Sanghavi; K Bjornard; J Bodurtha
Journal:  Ann Oncol       Date:  2013-10       Impact factor: 32.976

4.  Establishing effective registration systems in resource-limited settings: cancer registration in Kumasi, Ghana.

Authors:  Kieran S O'Brien; Amr S Soliman; Baffour Awuah; Evelyn Jiggae; Ernest Osei-Bonsu; Solomon Quayson; Ernest Adjei; Silpa S Thaivalappil; Frank Abantanga; Sofia D Merajver
Journal:  J Registry Manag       Date:  2013

5.  Stage at breast cancer diagnosis and distance from diagnostic hospital in a periurban setting: a South African public hospital case series of over 1,000 women.

Authors:  Caroline Dickens; Maureen Joffe; Judith Jacobson; Francois Venter; Joachim Schüz; Herbert Cubasch; Valerie McCormack
Journal:  Int J Cancer       Date:  2014-04-07       Impact factor: 7.396

Review 6.  Epidemiology, biology, and treatment of triple-negative breast cancer in women of African ancestry.

Authors:  Abenaa M Brewster; Mariana Chavez-MacGregor; Powel Brown
Journal:  Lancet Oncol       Date:  2014-11-24       Impact factor: 41.316

7.  Attitudes and Barriers to Research Among Oncology Trainees in East Africa.

Authors:  Fidel Rubagumya; Sarah K Nyagabona; Khadija H Msami; Achille Manirakiza; Ahuka N Longombe; Theoneste Maniragaba; Hilary Chan; Alan Paciorek; Li Zhang; Emmanuel Balandya; Leyna H Germana; Elia J Mmbaga; Nazima Dharsee; Katherine Van Loon
Journal:  Oncologist       Date:  2019-03-22

8.  Human immunodeficiency virus and cancer. A population of HIV-infected patients at Hospital de Santa Maria and predictors of cancer.

Authors:  Lígia Sofia Fernandes
Journal:  Germs       Date:  2012-06-01

9.  Researchers' Perspectives on Informed Consent and Ethical Review of Biobank Research in South Africa: A Cross-Sectional Study.

Authors:  Erisa Mwaka; Lyn Horn
Journal:  J Empir Res Hum Res Ethics       Date:  2019-08-05       Impact factor: 1.742

10.  An Insight Into Cervical Cancer Screening and Treatment Capacity in Sub Saharan Africa.

Authors:  Jenell S Coleman; Michelle S Cespedes; Susan Cu-Uvin; Rose J Kosgei; May Maloba; Jean Anderson; Timothy Wilkin; Antoine Jaquet; Julia Bohlius; Kathryn Anastos; Kara Wools-Kaloustian
Journal:  J Low Genit Tract Dis       Date:  2016-01       Impact factor: 1.925

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