Literature DB >> 2179201

The antimicrobial activity of fusidic acid.

L Verbist1.   

Abstract

Fusidic acid, a fusidane that interferes with protein synthesis via the translocase enzyme, is mainly notable for its activity against staphylococci, coagulase-positive and negative, whether or not they are resistant to methicillin and related penicillins. It is also active against corynebacteria and against many genera of strict anaerobes and microaerophiles. Mutants showing resistance, by more than one mechanism, may readily be selected in vitro. Combination of fusidic acid with other antibiotics generally gives addition or indifference, but also delays emergence of resistant mutants.

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Year:  1990        PMID: 2179201     DOI: 10.1093/jac/25.suppl_b.1

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN: 0305-7453            Impact factor:   5.790


  21 in total

1.  Fusidic acid is highly active against extracellular and intracellular Mycobacterium leprae.

Authors:  S G Franzblau; A N Biswas; E B Harris
Journal:  Antimicrob Agents Chemother       Date:  1992-01       Impact factor: 5.191

2.  Identification of steroid-like natural products as antiplasmodial agents by 2D and 3D similarity-based virtual screening.

Authors:  Elumalai Pavadai; Gurminder Kaur; Sergio Wittlin; Kelly Chibale
Journal:  Medchemcomm       Date:  2017-03-22       Impact factor: 3.597

Review 3.  Antibiotic prophylaxis in craniotomy: a review.

Authors:  Weiming Liu; Ming Ni; Yuewei Zhang; Rob J M Groen
Journal:  Neurosurg Rev       Date:  2014-02-13       Impact factor: 3.042

4.  Activity of antimicrobial peptides, alone or combined with conventional antibiotics, against Staphylococcus aureus isolated from the airways of cystic fibrosis patients.

Authors:  Katarzyna Garbacz; Wojciech Kamysz; Lidia Piechowicz
Journal:  Virulence       Date:  2016-07-22       Impact factor: 5.882

5.  Fusidic acid induced jaundice.

Authors:  M Haddad; S Shabat; A Koren; E Stelman; A Zelikovski
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1993-09       Impact factor: 3.267

Review 6.  Fusidic Acid: A Bacterial Elongation Factor Inhibitor for the Oral Treatment of Acute and Chronic Staphylococcal Infections.

Authors:  Prabhavathi Fernandes
Journal:  Cold Spring Harb Perspect Med       Date:  2016-01-04       Impact factor: 6.915

7.  Interaction of fusidic acid with lipid membranes: Implications to the mechanism of antibiotic activity.

Authors:  Emma Falck; Jari T Hautala; Mikko Karttunen; Paavo K J Kinnunen; Michael Patra; Heikki Saaren-Seppälä; Ilpo Vattulainen; Susanne K Wiedmer; Juha M Holopainen
Journal:  Biophys J       Date:  2006-06-16       Impact factor: 4.033

8.  The management of infection and colonization due to methicillin-resistant Staphylococcus aureus: A CIDS/CAMM position paper.

Authors:  Andrew E Simor; Mark Loeb
Journal:  Can J Infect Dis       Date:  2004-01

9.  Randomized placebo-controlled trial of single-dose antibiotic prophylaxis with fusidic acid in neurosurgery.

Authors:  T Mindermann; W Zimmerli; O Gratzl
Journal:  Acta Neurochir (Wien)       Date:  1993       Impact factor: 2.216

10.  Penetration of fusidic acid into human brain tissue and cerebrospinal fluid.

Authors:  T Mindermann; W Zimmerli; Z Rajacic; O Gratzl
Journal:  Acta Neurochir (Wien)       Date:  1993       Impact factor: 2.216

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