Literature DB >> 21790213

Taxanes: promising anti-cancer drugs.

Nilufer Jasmine Selimah Fauzee1.   

Abstract

Taxanes are amongst the most promising antitumor agents available at hand today, of increasing importance in Asia given that cancer is now one of the major public health problems which needs to be dealt urgently for the benefit of affected patients. Several ongoing experimental and clinical trials have supported the fact that even with their side effects and poor solubilities, taxanes are still the first lines of treatment chosen for breast, ovary, lung and other metastatic cancers. Prolonging the life of cancer patients is the main aim of all researchers, scientists, pharmaceutical companies and clinicians; therefore this review emphasizes the mechanisms of action of taxanes and how they can play an important role in palliative treatment if not applied for curative purposes, hence being considered a boon for cancer management.

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Year:  2011        PMID: 21790213

Source DB:  PubMed          Journal:  Asian Pac J Cancer Prev        ISSN: 1513-7368


  18 in total

Review 1.  Herbal medicine as inducers of apoptosis in cancer treatment.

Authors:  Elham Safarzadeh; Siamak Sandoghchian Shotorbani; Behzad Baradaran
Journal:  Adv Pharm Bull       Date:  2014-08-25

2.  Dynamic Diffuse Optical Tomography for Monitoring Neoadjuvant Chemotherapy in Patients with Breast Cancer.

Authors:  Jacqueline E Gunther; Emerson A Lim; Hyun K Kim; Molly Flexman; Mirella Altoé; Jessica A Campbell; Hanina Hibshoosh; Katherine D Crew; Kevin Kalinsky; Dawn L Hershman; Andreas H Hielscher
Journal:  Radiology       Date:  2018-02-12       Impact factor: 11.105

3.  Barley grass extract causes apoptosis of cancer cells by increasing intracellular reactive oxygen species production.

Authors:  Sang Mi Woo; Sang-Chul Kwon; Seong Gyu Ko; Sung-Gook Cho
Journal:  Biomed Rep       Date:  2017-05-03

4.  Novel hydrophilic docetaxel (CQMU-0519) analogue inhibits proliferation and induces apoptosis in human A549 lung, SKVO3 ovarian and MCF7 breast carcinoma cell lines.

Authors:  N J S Fauzee; Y-L Wang; Z Dong; Q-G Li; T Wang; M T Mandarry; L Xu; J Pan
Journal:  Cell Prolif       Date:  2012-06-05       Impact factor: 6.831

5.  Application of Priming Strategy for Enhanced Paclitaxel Biosynthesis in Taxus × Media Hairy Root Cultures.

Authors:  Katarzyna Sykłowska-Baranek; Grażyna Sygitowicz; Agata Maciejak-Jastrzębska; Agnieszka Pietrosiuk; Anna Szakiel
Journal:  Cells       Date:  2022-06-29       Impact factor: 7.666

6.  Synthesis and Biological Evaluation of a Biotinylated Paclitaxel With an Extra-Long Chain Spacer Arm.

Authors:  Lev G Lis; Mary A Smart; Anna Luchniak; Mohan L Gupta; Vadim J Gurvich
Journal:  ACS Med Chem Lett       Date:  2012-07-30       Impact factor: 4.345

7.  TaxKB: a knowledge base for new taxane-related drug discovery.

Authors:  Kasi Murugan; Sangeetha Shanmugasamy; Saleh Al-Sohaibani; Naga Vignesh; Kandavel Palanikannan; Antonydhason Vimala; Gopal Ramesh Kumar
Journal:  BioData Min       Date:  2015-06-28       Impact factor: 2.522

8.  Designing and Testing of Novel Taxanes to Probe the Highly Complex Mechanisms by Which Taxanes Bind to Microtubules and Cause Cytotoxicity to Cancer Cells.

Authors:  Marc St George; Ahmed T Ayoub; Asok Banerjee; Cassandra D M Churchill; Philip Winter; Mariusz Klobukowski; Carol E Cass; Richard F Ludueña; Jack A Tuszynski; Sambasivarao Damaraju
Journal:  PLoS One       Date:  2015-06-08       Impact factor: 3.240

9.  Paclitaxel-Loaded Folate-Targeted Albumin-Alginate Nanoparticles Crosslinked with Ethylenediamine. Synthesis and In Vitro Characterization.

Authors:  Ana María Martínez-Relimpio; Marta Benito; Elena Pérez-Izquierdo; César Teijón; Rosa María Olmo; María Dolores Blanco
Journal:  Polymers (Basel)       Date:  2021-06-24       Impact factor: 4.329

10.  Nanoparticulated docetaxel exerts enhanced anticancer efficacy and overcomes existing limitations of traditional drugs.

Authors:  Jinhyang Choi; Eunjung Ko; Hye-Kyung Chung; Jae Hee Lee; Eun Jin Ju; Hyun Kyung Lim; Intae Park; Kab-Sig Kim; Joo-Hwan Lee; Woo-Chan Son; Jung Shin Lee; Joohee Jung; Seong-Yun Jeong; Si Yeol Song; Eun Kyung Choi
Journal:  Int J Nanomedicine       Date:  2015-09-29
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