Literature DB >> 21785757

A novel membrane-permeant cADPR antagonist modified in the pyrophosphate bridge.

N Qi1, K Jung, M Wang, L X Na, Z J Yang, L R Zhang, A H Guse, L H Zhang.   

Abstract

A concise method for the formation of cyclopyrophosphate of cIDPRE as well as sulfur and selenium-substituted pyrophosphate cIDPRE analogues (P(1)(S)-cIDPRE, P(1)(Se)-cIDPRE, P(2)(S)-cIDPRE and P(2)(Se)-cIDPRE) was reported and one of the P(S)-diastereoisomers, P(1)(S)-cIDPRE-1, is a novel membrane-permeant cADPR antagonist. This journal is © The Royal Society of Chemistry 2011

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Year:  2011        PMID： 21785757     DOI： 10.1039/c1cc13062e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

1.  A novel fluorescent cell membrane-permeable caged cyclic ADP-ribose analogue.

Authors:  Pei-Lin Yu; Zhe-Hao Zhang; Bai-Xia Hao; Yong-Juan Zhao; Li-He Zhang; Hon-Cheung Lee; Liangren Zhang; Jianbo Yue
Journal:  J Biol Chem       Date:  2012-06-01       Impact factor: 5.157

2.  'Click cyclic ADP-ribose': a neutral second messenger mimic.

Authors:  Joanna M Swarbrick; Richard Graeff; Clive Garnham; Mark P Thomas; Antony Galione; Barry V L Potter
Journal:  Chem Commun (Camb)       Date:  2014-01-23       Impact factor: 6.222

3.  Synthesis of cyclic N (1)-pentylinosine phosphate, a new structurally reduced cADPR analogue with calcium-mobilizing activity on PC12 cells.

Authors:  Ahmed Mahal; Stefano D'Errico; Nicola Borbone; Brunella Pinto; Agnese Secondo; Valeria Costantino; Valentina Tedeschi; Giorgia Oliviero; Vincenzo Piccialli; Gennaro Piccialli
Journal:  Beilstein J Org Chem       Date:  2015-12-22       Impact factor: 2.883

4.  Synthesis and calcium mobilization activity of cADPR analogues which integrate nucleobase, northern and southern ribose modifications.

Authors:  Yue Zhou; Peilin Yu; Hongwei Jin; Zhenjun Yang; Jianbo Yue; Liangren Zhang; Lihe Zhang
Journal:  Molecules       Date:  2012-04-10       Impact factor: 4.411

5.  New Linear Precursors of cIDPR Derivatives as Stable Analogs of cADPR: A Potent Second Messenger with Ca2+-Modulating Activity Isolated from Sea Urchin Eggs.

Authors:  Stefano D'Errico; Emy Basso; Andrea Patrizia Falanga; Maria Marzano; Tullio Pozzan; Vincenzo Piccialli; Gennaro Piccialli; Giorgia Oliviero; Nicola Borbone
Journal:  Mar Drugs       Date:  2019-08-17       Impact factor: 5.118

6.  Novel formulation of c-di-GMP with cytidinyl/cationic lipid reverses T cell exhaustion and activates stronger anti-tumor immunity.

Authors:  Xiaotong Yu; Jing Yu; Hong Dai; Chenyun Deng; Xudong Sun; Sijie Long; Zhujun Jiang; Hongyan Jin; Zhu Guan; Zhenjun Yang
Journal:  Theranostics       Date:  2022-09-11       Impact factor: 11.600
  6 in total

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