Literature DB >> 21784782

Do general practitioners' consultation rates influence their prescribing patterns of antibiotics for acute respiratory tract infections?

Svein Gjelstad1, Jørund Straand, Ingvild Dalen, Arne Fetveit, Hanne Strøm, Morten Lindbæk.   

Abstract

OBJECTIVES: To examine general practitioners' (GPs') antibiotic prescribing patterns for acute respiratory tract infections (ARTIs) as compared with national guidelines. We also wanted to explore possible predictors of antibiotic prescription patterns.
METHODS: Observational study based on prescription data from 440 Norwegian GPs in December 2004 through to November 2005. Outcome measures were the type and frequency of antibiotic prescriptions for various ARTI diagnoses, with patients' and GPs' characteristics as explanatory variables.
RESULTS: In the study period, the 440 GPs treated a total of 142 900 ARTI episodes. In 33.5% [95% confidence interval (CI): 31.9%-35.1%] of these episodes an antibiotic was issued, of which penicillin V (pcV) accounted for 41.2% (95% CI: 37.4%-44.9%). GPs with a high number of total annual encounters had higher antibiotic prescription rates for ARTIs and used more non-pcV antibiotics compared with GPs with fewer annual patient encounters. GPs in the highest quintile with respect to the total annual encounter rate had 1.6 times the odds of prescribing antibiotics compared with GPs in the lowest quintile. Correspondingly, the odds of choosing a non-pcV antibiotic were 2.8 times higher in the top quintile of GPs compared with GPs in the bottom quintile with respect to antibiotic prescription rates.
CONCLUSIONS: ARTIs are frequently treated with antibiotics and often with broader spectrum agents than pcV, which is the recommended first-line antibiotic in the Norwegian guidelines. GPs with a high practice activity are, in general, more liberal with respect to the prescription of antibiotics for ARTIs, and the higher the antibiotic prescription rate, the larger the share of non-pcV agents.

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Year:  2011        PMID: 21784782     DOI: 10.1093/jac/dkr295

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN: 0305-7453            Impact factor:   5.790


  37 in total

1.  Mycoplasma pneumoniae detection causes excess antibiotic use in Norwegian general practice: a retrospective case-control study.

Authors:  Mats Foshaug; Maria Vandbakk-Rüther; Dagfinn Skaare; Nils Grude; Morten Lindbæk
Journal:  Br J Gen Pract       Date:  2015-02       Impact factor: 5.386

2.  Pregnancy outcome after gestational exposure to erythromycin - a population-based register study from Norway.

Authors:  Maria Romøren; Morten Lindbæk; Hedvig Nordeng
Journal:  Br J Clin Pharmacol       Date:  2012-12       Impact factor: 4.335

Review 3.  Behavioral Economics and Ambulatory Antibiotic Stewardship: A Narrative Review.

Authors:  Alexandra R Richards; Jeffrey A Linder
Journal:  Clin Ther       Date:  2021-10-23       Impact factor: 3.637

4.  Effects on antibiotic dispensing rates of interventions to promote delayed prescribing for respiratory tract infections in primary care.

Authors:  Sigurd Høye; Svein Gjelstad; Morten Lindbæk
Journal:  Br J Gen Pract       Date:  2013-11       Impact factor: 5.386

5.  Prescription peer academic detailing to reduce inappropriate prescribing for older patients: a cluster randomised controlled trial.

Authors:  Sture Rognstad; Mette Brekke; Arne Fetveit; Ingvild Dalen; Jørund Straand
Journal:  Br J Gen Pract       Date:  2013-08       Impact factor: 5.386

6.  Antibiotic prescribing in patients with acute rhinosinusitis is not in agreement with European recommendations.

Authors:  Lars Christian Jørgensen; Sarah Friis Christensen; Gloria Cordoba Currea; Carl Llor; Lars Bjerrum
Journal:  Scand J Prim Health Care       Date:  2013-06       Impact factor: 2.581

7.  Are children carrying the burden of broad-spectrum antibiotics in general practice? Prescription pattern for paediatric outpatients with respiratory tract infections in Norway.

Authors:  Guro Haugen Fossum; Morten Lindbæk; Svein Gjelstad; Ingvild Dalen; Kari J Kværner
Journal:  BMJ Open       Date:  2013-01-07       Impact factor: 2.692

Review 8.  Antibiotic Resistance: What are the Opportunities for Primary Care in Alleviating the Crisis?

Authors:  Malene Plejdrup Hansen; Tammy C Hoffmann; Amanda R McCullough; Mieke L van Driel; Chris B Del Mar
Journal:  Front Public Health       Date:  2015-02-24

9.  Identification of cultural determinants of antibiotic use cited in primary care in Europe: a mixed research synthesis study of integrated design "Culture is all around us".

Authors:  Pia Touboul-Lundgren; Siri Jensen; Johann Drai; Morten Lindbæk
Journal:  BMC Public Health       Date:  2015-09-17       Impact factor: 3.295

10.  Improving antibiotic prescribing in acute respiratory tract infections: cluster randomised trial from Norwegian general practice (prescription peer academic detailing (Rx-PAD) study).

Authors:  Svein Gjelstad; Sigurd Høye; Jørund Straand; Mette Brekke; Ingvild Dalen; Morten Lindbæk
Journal:  BMJ       Date:  2013-07-26
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