Literature DB >> 21783242

Allergic rhinitis.

Alexander N Greiner1, Peter W Hellings, Guiseppina Rotiroti, Glenis K Scadding.   

Abstract

Allergic rhinitis is a very common disorder that affects people of all ages, peaking in the teenage years. It is frequently ignored, underdiagnosed, misdiagnosed, and mistreated, which not only is detrimental to health but also has societal costs. Although allergic rhinitis is not a serious illness, it is clinically relevant because it underlies many complications, is a major risk factor for poor asthma control, and affects quality of life and productivity at work or school. Management of allergic rhinitis is best when directed by guidelines. A diagnostic trial of a pharmacotherapeutic agent could be started in people with clinically identified allergic rhinitis; however, to confirm the diagnosis, specific IgE reactivity needs to be recorded. Documented IgE reactivity has the added benefit of guiding implementation of environmental controls, which could substantially ameliorate symptoms of allergic rhinitis and might prevent development of asthma, especially in an occupational setting. Many classes of drug are available, effective, and safe. In meta-analyses, intranasal corticosteroids are superior to other treatments, have a good safety profile, and treat all symptoms of allergic rhinitis effectively. First-generation antihistamines are associated with sedation, psychomotor retardation, and reduced academic performance. Only immunotherapy with individually targeted allergens has the potential to alter the natural history of allergic rhinitis. Patients' education is a vital component of treatment. Even with the best pharmacotherapy, one in five affected individuals remains highly symptomatic, and further research is needed in this area.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 21783242     DOI: 10.1016/S0140-6736(11)60130-X

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  174 in total

Review 1.  Allergic rhinitis: an updated overview.

Authors:  Sverre K Steinsvaag
Journal:  Curr Allergy Asthma Rep       Date:  2012-04       Impact factor: 4.806

2.  Biomarkers of respiratory allergy in laboratory animal care workers: an observational study.

Authors:  Federica Tafuro; Luisella Selis; Matteo Goldoni; Mariarita Stendardo; Paola Mozzoni; Erminia Ridolo; Piera Boschetto; Massimo Corradi
Journal:  Int Arch Occup Environ Health       Date:  2018-06-01       Impact factor: 3.015

3.  Data quality from a longitudinal study of adolescent health at schools near industrial livestock facilities.

Authors:  Virginia T Guidry; Christine L Gray; Amy Lowman; Devon Hall; Steve Wing
Journal:  Ann Epidemiol       Date:  2015-03-18       Impact factor: 3.797

4.  Azelastine enhances the clinical efficacy of glucocorticoid by modulating MKP-1 expression in allergic rhinitis.

Authors:  Xi Luo; Renqiang Ma; Xingmei Wu; Desheng Xian; Jian Li; Zhonglin Mou; Huabin Li
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-07-25       Impact factor: 2.503

Review 5.  [Personalized medicine in allergology].

Authors:  W Pfützner; J Pickert; C Möbs
Journal:  Hautarzt       Date:  2019-01       Impact factor: 0.751

6.  Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

Authors:  Johannes Waage; Marie Standl; John A Curtin; Leon E Jessen; Jonathan Thorsen; Chao Tian; Nathan Schoettler; Carlos Flores; Abdel Abdellaoui; Tarunveer S Ahluwalia; Alexessander C Alves; Andre F S Amaral; Josep M Antó; Andreas Arnold; Amalia Barreto-Luis; Hansjörg Baurecht; Catharina E M van Beijsterveldt; Eugene R Bleecker; Sílvia Bonàs-Guarch; Dorret I Boomsma; Susanne Brix; Supinda Bunyavanich; Esteban G Burchard; Zhanghua Chen; Ivan Curjuric; Adnan Custovic; Herman T den Dekker; Shyamali C Dharmage; Julia Dmitrieva; Liesbeth Duijts; Markus J Ege; W James Gauderman; Michel Georges; Christian Gieger; Frank Gilliland; Raquel Granell; Hongsheng Gui; Torben Hansen; Joachim Heinrich; John Henderson; Natalia Hernandez-Pacheco; Patrick Holt; Medea Imboden; Vincent W V Jaddoe; Marjo-Riitta Jarvelin; Deborah L Jarvis; Kamilla K Jensen; Ingileif Jónsdóttir; Michael Kabesch; Jaakko Kaprio; Ashish Kumar; Young-Ae Lee; Albert M Levin; Xingnan Li; Fabian Lorenzo-Diaz; Erik Melén; Josep M Mercader; Deborah A Meyers; Rachel Myers; Dan L Nicolae; Ellen A Nohr; Teemu Palviainen; Lavinia Paternoster; Craig E Pennell; Göran Pershagen; Maria Pino-Yanes; Nicole M Probst-Hensch; Franz Rüschendorf; Angela Simpson; Kari Stefansson; Jordi Sunyer; Gardar Sveinbjornsson; Elisabeth Thiering; Philip J Thompson; Maties Torrent; David Torrents; Joyce Y Tung; Carol A Wang; Stephan Weidinger; Scott Weiss; Gonneke Willemsen; L Keoki Williams; Carole Ober; David A Hinds; Manuel A Ferreira; Hans Bisgaard; David P Strachan; Klaus Bønnelykke
Journal:  Nat Genet       Date:  2018-07-16       Impact factor: 38.330

7.  Epithelial cells expressed IL-33 to promote degranulation of mast cells through inhibition on ST2/PI3K/mTOR-mediated autophagy in allergic rhinitis.

Authors:  Jia-Bin Nian; Min Zeng; Jing Zheng; Lian-Ya Zeng; Zhi Fu; Qiu-Ju Huang; Xin Wei
Journal:  Cell Cycle       Date:  2020-04-16       Impact factor: 4.534

8.  The amendatory effect of hesperidin and thymol in allergic rhinitis: an ovalbumin-induced rat model.

Authors:  Korhan Kilic; Muhammed Sedat Sakat; Serkan Yildirim; Fatih Mehmet Kandemir; Mustafa Sitki Gozeler; Muhammed Bahaeddin Dortbudak; Sefa Kucukler
Journal:  Eur Arch Otorhinolaryngol       Date:  2018-11-28       Impact factor: 2.503

9.  Endotypes and phenotypes of chronic rhinosinusitis: a PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology.

Authors:  Cezmi A Akdis; Claus Bachert; Cemal Cingi; Mark S Dykewicz; Peter W Hellings; Robert M Naclerio; Robert P Schleimer; Dennis Ledford
Journal:  J Allergy Clin Immunol       Date:  2013-04-12       Impact factor: 10.793

10.  Using parental perceptions of childhood allergic rhinitis to inform primary care management.

Authors:  Jane M Garbutt; Randall Sterkel; Kathy B Mullen; Bridget Conlon; Erin Leege; Gordon Bloomberg; Robert C Strunk
Journal:  Clin Pediatr (Phila)       Date:  2014-05-06       Impact factor: 1.168

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